Fibroblast Activation Protein-Targeted NIR-I/II Fluorescence Imaging for Detecting Hepatocellular Carcinoma

A Novel Near-Infrared Fluorescence Imaging Study Targeting Hepatocellular Carcinoma (HCC) Hepatocellular carcinoma (HCC) ranks as the sixth most common malignancy and the third leading cause of cancer-related mortality worldwide. Statistics indicate that the postoperative recurrence rate of HCC reaches as high as 80%, with liver fibrosis or cirrhos...

A Proof-of-Concept Study for Precise Mapping of Pigmented Basal Cell Carcinoma in Asian Skin Using Multispectral Optoacoustic Tomography Imaging with Level Set Segmentation

A Proof-of-Concept Study for Precise Mapping of Pigmented Basal Cell Carcinoma in Asian Skin Using Multispectral Optoacoustic Tomography Imaging with Level Set Segmentation

A New Approach to Skin Cancer Diagnosis: Research on Photoacoustic Imaging with Level Set Segmentation Algorithm In recent years, with global population aging and environmental changes, the incidence rate of skin cancer has been climbing annually. As a significant public health issue, skin cancer primarily manifests in non-melanoma types like squam...

Protein-functionalized and intrinsically radiolabeled 188Re oxide nanoparticles: advancing cancer therapy through concurrent radio-photothermal effects

Protein-Functionalized and Intrinsically Radiolabeled [188Re]ReOx Nanoparticles: Breakthrough Application in Multimodal Synergistic Cancer Therapy Cancer remains one of the leading causes of death globally, despite significant progress in medical science over the past few decades. However, early detection and treatment methods still face significan...

Development of a Novel Molecular Probe for Visualizing Mesothelin in Tumors

Development of a Molecular Probe for Tumor-Associated Protein Mesothelin Based on PET Imaging Technology Research Background In recent years, mesothelin (MSLN) has become a key focus in cancer research and diagnostics. Mesothelin is a membrane-bound glycoprotein highly expressed on the surface of various malignancies, including ovarian, pancreatic,...

PSMA PET/CT-based Multimodal Deep Learning Model for Accurate Prediction of Pelvic Lymph-Node Metastases in Prostate Cancer

In-depth Analysis of PSMA PET/CT-based Multimodal Deep Learning Model for Predicting Lymph Node Metastases in Prostate Cancer Patients Background Prostate cancer (PCA) is one of the most common malignant tumors in men and a leading cause of cancer-related deaths. In clinically localized prostate cancer patients, extended pelvic lymph node dissectio...

The Practical Advantage of One-Day Dual-Tracer Examination in Neuroendocrine Neoplasms Using Low-Activity LAFOV PET Imaging

Breakthrough in Nuclear Medicine and Molecular Imaging: European Study Reveals Application of One-Day Dual-Tracer PET/CT Imaging in Neuroendocrine Tumors In the field of nuclear medicine, neuroendocrine neoplasms (NENs), known for their heterogeneity and complexity, have consistently been a focal point of research. A team from Tübingen, Germany, ha...