The Practical Advantage of One-Day Dual-Tracer Examination in Neuroendocrine Neoplasms Using Low-Activity LAFOV PET Imaging

Breakthrough in Nuclear Medicine and Molecular Imaging: European Study Reveals Application of One-Day Dual-Tracer PET/CT Imaging in Neuroendocrine Tumors In the field of nuclear medicine, neuroendocrine neoplasms (NENs), known for their heterogeneity and complexity, have consistently been a focal point of research. A team from Tübingen, Germany, ha...

An Explainable Transformer Model Integrating PET and Tabular Data for Histologic Grading and Prognosis of Follicular Lymphoma: A Multi-Institutional Digital Biopsy Study

A Transformer Model Integrating PET Imaging and Clinical Data: A Multicenter Digital Biopsy Study for Predicting Pathological Grading and Prognosis of Follicular Lymphoma Academic Background Follicular Lymphoma (FL) is the most common indolent Non-Hodgkin Lymphoma in Western countries, accounting for approximately 30% of newly diagnosed cases. Acco...

Impact of FAPI Molar Dose on Targeted PET Imaging and Therapy in Mouse Syngeneic Tumor Models

Background In recent years, significant progress has been made in the field of cancer diagnosis and treatment, particularly in technologies based on molecular imaging and targeted radiotherapy. Among these, Fibroblast Activation Protein (FAP), a biomarker highly expressed in the tumor microenvironment, has garnered widespread attention. FAP is prim...

Clinical impact of an explainable radiomics model with amino acid PET imaging: application to the diagnosis of aggressive gliomas

Application of Explainable Machine Learning in Amino Acid PET Imaging for Glioma Diagnosis Academic Background Gliomas are among the most common malignant tumors of the central nervous system, with their diagnosis and treatment strategies typically relying on histopathological analysis. However, histopathology has limitations such as being highly i...

Ultra-Fast PSMA-PET Staging in Prostate Cancer Enhanced by Artificial Intelligence

Application of AI-Enhanced Ultra-Fast PSMA-PET in Prostate Cancer Staging Academic Background Prostate cancer is one of the most common cancers among men globally, and accurate diagnosis and staging are crucial for treatment decision-making. Prostate-specific membrane antigen (PSMA) positron emission tomography (PET) has become a standard examinati...

Overexpression of REF-1 in Neovascular Eye Diseases and Its Inhibition by a Novel Compound

REF-1 Overexpression in Neovascular Eye Diseases and Therapeutic Targeting with a Novel Inhibitor Academic Background Neovascular age-related macular degeneration (nAMD) is a common blinding eye disease predominantly affecting individuals aged 60 years and older. nAMD is characterized by the formation of subretinal neovascularization, leading to re...