The Impact of Glioblastoma Differentiation on Blood-Brain Barrier Permeability Background Introduction Glioblastoma Multiforme (GBM) is a highly aggressive brain tumor, and its treatment is extremely challenging due to its complex biological characteristics and the presence of the Blood-Brain Barrier (BBB). The BBB is a complex structure composed o...

Non-Invasive Imaging Technique for Evaluating Trans-Barrier Water Exchange in the Choroid Plexus Background Introduction The choroid plexus (CP) is a critical site for cerebrospinal fluid (CSF) production and an essential component of the blood-cerebrospinal fluid barrier (BCSFB). The CP regulates CSF secretion and absorption, maintaining brain hom...

Challenges to Mediterranean Fagaceae Ecosystems Affected by Phytophthora cinnamomi and Climate Change Academic Background The Mediterranean Fagaceae ecosystems, including oak trees (Quercus ilex and Quercus suber) and chestnut trees (Castanea sativa), are vital ecological and economic resources in southern Europe. However, in recent years, these ec...

Global Progress in Quantifying Fire Behavior Characteristics in Forests and Shrublands Academic Background Wildland fire is a complex natural phenomenon involving interactions among chemical, physical, and biological processes. Due to its free-spreading nature, destructive energy fluxes, and hazardous environment, studying wildland fire is highly c...

Trade-offs and Trait Integration in Tree Phenotypes Academic Background With the intensification of global climate change and biodiversity loss, the sustainable management of forest ecosystems has become increasingly important. As a key component of forest ecosystems, the trade-offs and integration of tree phenotypic traits (such as growth, reprodu...

Environmental Sensitivity and Impact of Climate Change on Phenology in Temperate Deciduous Forests Academic Background The impact of climate change on global ecosystems is becoming increasingly significant, particularly in the phenological changes of temperate and boreal forests. Phenology, the study of seasonal events in the life cycles of plants,...

Forest Tree Virome as a Source of Tree Diseases and Biological Control Academic Background The health of forest ecosystems is crucial for global ecological balance and economic development. However, the health of forest trees is threatened by various pathogens, including fungi, oomycetes, bacteria, viruses, as well as insect and nematode pests. Alt...

Responses of Tropical Tree Seedlings to Nutrient Addition: A Meta-Analysis to Understand Future Changes in Tropical Forest Dynamics Academic Background Tropical forests are critical components of global biodiversity and ecosystem functions. However, due to the impacts of human activities and climate change, tropical forests are facing unprecedented...

Forest Resilience and the Role of Invasive Tree Species under Climate Change Academic Background With the intensification of global climate change, the resilience of forest ecosystems is under severe threat. Climate change has led to a decline in the vitality of major native tree species, weakening the ability of forests to provide ecosystem servic...

Advances in Spatial Forest Planning: Methods, Challenges, and Future Directions Academic Background Forest management planning is a critical tool for ensuring the sustainable use of forest resources. With the increasing global demand for forest products and ecosystem services, traditional forest planning methods are no longer sufficient to meet com...