Infantile Hemangioma (IH) is the most common benign vascular tumor in children, with an incidence rate of approximately 4%-10%. Although most IH cases resolve spontaneously, some cases may lead to permanent pigmentation, fibrous tissue accumulation, and scarring, affecting the appearance and quality of life of children. Additionally, certain IH cas...

Colorectal Cancer (CRC) is one of the most prevalent malignancies globally, with its prognosis closely related to immune responses within the tumor microenvironment. In recent years, Tertiary Lymphoid Structures (TLS), as an essential component of the tumor microenvironment, have been associated with favorable patient outcomes. TLS are aggregates o...

Academic Background Ulcerative Colitis (UC) is a chronic inflammatory bowel disease often accompanied by various extraintestinal complications, among which pulmonary infections are particularly severe. Although previous studies have indicated interactions between the intestinal and pulmonary immune systems, the specific mechanisms involving neutrop...

Cervical Cancer (CC) is the fourth most common malignant tumor among women worldwide, particularly in low- and middle-income countries, where its incidence and mortality rates remain high. According to statistics, there were over 600,000 new cases and more than 340,000 deaths globally in 2020. The primary cause of cervical cancer is the persistent ...

Nasopharyngeal carcinoma (NPC) is a malignant tumor originating from the epithelial lining of the nasopharynx, characterized by a distinct geographical distribution, particularly with high incidence rates in Southeast Asia and Southern China. Despite significant progress in NPC treatment in recent years, the prognosis for patients remains poor, esp...

Breast cancer is one of the most common malignancies among women worldwide. Although early intervention and appropriate treatment have significantly improved patient survival rates, approximately 30% of cases still experience recurrence and distant metastasis, resulting in a 5-year survival rate of less than 23%. Traditional clinical prediction met...

Inflammatory Bowel Disease (IBD) is a chronic, relapsing inflammatory disorder of the gastrointestinal tract, primarily including Ulcerative Colitis (UC) and Crohn’s Disease (CD). In recent years, the incidence of IBD has been on the rise globally, placing a significant burden on healthcare systems. Although it is widely accepted that IBD is associ...

Lung cancer is one of the leading causes of death worldwide, with lung squamous cell carcinoma (LUSC) being a subtype of non-small cell lung cancer (NSCLC), accounting for 20%-30% of all NSCLC cases. Despite significant advancements in lung cancer treatment in recent years, LUSC still lacks effective targeted therapies, and patients have a poor pro...

Aging is one of the major risk factors for a variety of chronic diseases and death. However, chronological age does not fully reflect individual differences in the biological aging process. Phenotypic age is a composite score based on routine clinical markers, used to differentiate individuals within the same age group who have varying risks of dis...

Academic Background Pancreatectomy is an important treatment for pancreatic diseases, but postoperative pancreatic fistula (POPF) is a common and serious complication, with an incidence rate as high as 20%. POPF not only prolongs hospital stays and increases medical costs but is also closely associated with increased postoperative mortality. Theref...