The Geometry of Correlated Variability Leads to Highly Suboptimal Discriminative Sensory Coding

Medicine, Neurology, Life Sciences, Biophysics,
correlated variability   discriminative sensory coding   neurophysiology   null models   sensory coding  

Correlated Variability in the Brain Leads to Highly Suboptimal Sensory Coding Academic Background The brain perceives the world through the activity of neural populations, but it remains unclear whether the computational goal of sensory coding is to support the discrimination of sensory stimuli or to generate an internal model of the sensory world....

A Single Exposure to Prolonged Flexor Carpi Radialis Muscle Vibration Increases Sensorimotor Cortical Areas Activity

Medicine, Neurology,
vibration   sensorimotor cortex   brain plasticity   electroencephalography   neurophysiology  

Effects of Local Vibration on Sensorimotor Cortical Activity Background Introduction Local Vibration (LV) is a technique that applies high-frequency (≥100 Hz) and low-amplitude ( mm) vibrations to muscles or tendons. Studies have shown that LV can promote brain plasticity through repeated activation of Ia afferents, but the specific mechanisms rema...

Insulin Activates Parasympathetic Hepatic-Related Neurons of the Paraventricular Nucleus of the Hypothalamus Through mTOR Signaling

Medicine, Endocrinology, Neurology,
insulin   paraventricular nucleus of the hypothalamus   parasympathetic   hepatic glucose production   mTOR signaling  

Insulin Activates Hepatic-Related Neurons in the Paraventricular Nucleus of the Hypothalamus via mTOR Signaling Academic Background Glucose homeostasis is a critical physiological process for sustaining life, with the liver playing a central role in this regulation. The liver maintains blood glucose levels by modulating glycogen production and gluc...

Control of Movement: Latency and Amplitude of Catch-Up Saccades to Accelerating Targets

Medicine, Neurology, Ophthalmology,
catch-up saccades   retinal acceleration error   eye movement coordination   saccade programming   smooth pursuit  

The Impact of Retinal Acceleration Error on Catch-Up Saccades Research Background When humans track moving objects, they primarily rely on two types of eye movements: smooth pursuit and saccades. Smooth pursuit depends on visual motion signals, but when tracking errors accumulate, the brain initiates catch-up saccades to realign the gaze with the t...

The Serotonergic Psychedelic DOI Impairs Deviance Detection in the Auditory Cortex

Medicine, Psychiatry, Neurology, Clinical Psychology,
auditory cortex   deviance detection   psychedelics   serotonin   neural response variability  

The Impairment of Deviance Detection in the Auditory Cortex by DOI Academic Background Psychedelics are a class of psychoactive substances that can significantly alter perception, cognition, and mood. In recent years, psychedelics have shown potential applications in treating conditions such as depression, anxiety, and trauma-related disorders. How...

Dopamine Receptors D1, D2, and D4 Modulate Electrical Synapses and Excitability in the Thalamic Reticular Nucleus

Medicine, Neurology, Life Sciences, Biochemistry, Biophysics,
dopamine receptors   electrical synapses   thalamic reticular nucleus   excitability   neuromodulation  

The Regulatory Role of Dopamine Receptors in the Thalamic Reticular Nucleus: A Study on Neuronal Excitability and Electrical Synapses Academic Background The Thalamic Reticular Nucleus (TRN) is a crucial inhibitory neuronal network in the brain, responsible for regulating the transmission of sensory information between the thalamus and the cortex. ...