Magnetic Nanoplatform Based on CD26 Targeting and HSP90 Inhibition for Apoptosis and Ferroptosis-Mediated Elimination of Senescent Cells Academic Background With the intensification of population aging, the accumulation of senescent cells is considered a significant hallmark of aging and age-related diseases. Senescent cells are not only associated...

Enhancing Gene Delivery to Breast Cancer with Highly Efficient siRNA Loading and pH-Responsive Small Extracellular Vesicles Academic Background In recent years, small extracellular vesicles (sEVs) have become a hot topic in the field of drug delivery due to their natural origin and inherent homing properties. sEVs are lipid nanoparticles secreted b...

Supramolecular Hydrogels Driven by β-Sheet Fibrillating Peptides for Enhanced Diabetic Wound Healing Academic Background Diabetic wound healing is a global health issue. Due to microvascular complications and immune dysfunction caused by hyperglycemia, the wound healing process in diabetic patients is often severely hindered. Traditional treatments...

Sex Differences in Olfactory Behavior and Neurophysiology in Long Evans Rats Academic Background Olfaction plays a crucial role in the survival and reproduction of many species. Studies have shown that females exhibit greater sensitivity in certain olfactory behaviors compared to males. For example, human females outperform males in olfactory thres...

Computational Modeling Study on the Construction of Receptive Fields in Midget Ganglion Cells of Primate Retina Academic Background The midget pathway in the primate retina is the foundation for high spatial resolution and color perception in the visual system. A key feature of this pathway is the center-surround organization of the receptive field...

Correlated Variability in the Brain Leads to Highly Suboptimal Sensory Coding Academic Background The brain perceives the world through the activity of neural populations, but it remains unclear whether the computational goal of sensory coding is to support the discrimination of sensory stimuli or to generate an internal model of the sensory world....