Pancreatic cancer is a highly malignant tumor with an extremely low five-year survival rate, especially for patients with locally advanced pancreatic cancer (LAPC), who have limited treatment options and poor prognosis. LAPC is defined based on the degree of tumor contact with adjacent blood vessels and is often considered “unresectable” at diagnos...

Mastectomy is a common surgical procedure in the treatment of breast cancer, with approximately 55,000 women diagnosed with breast cancer each year in the UK, of whom up to 40% undergo mastectomy. Mastectomy has a profound impact on women’s physical and mental health, and the UK National Institute for Health and Care Excellence (NICE) recommends th...

Colorectal Cancer (CRC) is the third most common malignant tumor worldwide, and its prognosis assessment primarily relies on the TNM staging system. However, the current TNM staging system does not fully account for the presence and count of Tumor Deposits (TDs) in lymph node-positive colorectal cancer. Tumor deposits refer to discrete tumor nodule...

Breast cancer is one of the most common cancers among women worldwide, with over 56,000 women diagnosed annually in the UK. Despite advancements in treatment, approximately 40% of patients still undergo mastectomy. While mastectomy effectively controls cancer, it profoundly impacts patients’ quality of life. Many women describe mastectomy as a “dis...

With advances in anesthesia, surgery, and intensive care management, the short-term perioperative outcomes of surgical patients have significantly improved. However, an increasing number of studies are focusing on long-term outcomes directly related to patient prognosis, such as functional recovery or functional disability. Functional disability is...

Academic Background Malnutrition is a significant risk factor for postoperative complications, particularly in patients undergoing major abdominal surgery, where the incidence of malnutrition is high. However, there is currently no widely accepted tool for assessing malnutrition. Existing nutritional screening tools vary greatly in sensitivity and ...