Development and External Validation of Prediction Risk Scores (StrISK and NOFA) to Predict Immediate Surgical Need in Adhesive Small Bowel Obstruction: An Observational Prospective Multicentre Study

Medicine, Emergency Medicine, Gastroenterology,
Adhesive Small Bowel Obstruction   Prediction Model   Surgical Need   Multicentre Study   External Validation  

Background Introduction Adhesive Small Bowel Obstruction (ASBO) is one of the leading causes of emergency admissions, accounting for approximately 60% of all small bowel obstruction cases. ASBO is often caused by postoperative intra-abdominal adhesions, with patients presenting symptoms such as abdominal pain, vomiting, and constipation. While most...

Routine Anaesthesia Ward-Based Patient Visits in Surgery: 1-Year Outcomes of the TRACE Randomized Clinical Trial

Medicine, Anesthesiology,
anaesthesia ward visits   surgical outcomes   functional recovery   quality of life   randomized clinical trial  

In perioperative medicine, the long-term clinical and functional recovery of postoperative patients has always been a focus of research. Traditionally, postoperative complications, mortality, readmission rates, and reoperation rates have been the primary indicators for measuring surgical patient outcomes. However, as medical research deepens, an in...

Parathyroid Vascular Anatomy Using Intraoperative Mapping Angiography: The Paratlas Study

Medicine, Endocrinology,
parathyroid   vascular anatomy   thyroidectomy   vessel distribution   intraoperative mapping  

Academic Background The preservation of the parathyroid glands (PGs) during thyroidectomy is crucial, as postoperative hypoparathyroidism is a common complication of thyroid surgery, particularly after total thyroidectomy. Approximately 30%-40% of patients experience transient hypoparathyroidism, with 5%-10% developing permanent hypoparathyroidism....

Preoperative Stereotactic Radiotherapy to Prevent Pancreatic Fistula in High-Risk Patients Undergoing Pancreatoduodenectomy (FIBROPANC): Prospective Multicentre Phase II Single-Arm Trial

Medicine, Hepatobiliary System, Anesthesiology, Gastroenterology, Oncology,
pancreatic fistula   stereotactic radiotherapy   pancreatoduodenectomy   high-risk patients   fibrosis   safety   efficacy  

Pancreaticoduodenectomy is a common surgery for treating tumors of the pancreas and surrounding organs, but postoperative pancreatic fistula (POPF) is one of its major complications, especially in high-risk patients, where the incidence of POPF can be as high as 50%. POPF not only increases hospitalization time and medical costs but can also lead t...

Detecting Residual Disease After Neoadjuvant Chemoradiotherapy for Oesophageal Squamous Cell Carcinoma: Prospective Multicentre PRESINO Trial

Medicine, Oncology,
Oesophageal squamous cell carcinoma   Neoadjuvant chemoradiotherapy   Residual disease   Prospective study   Multicentre trial   Tumour recurrence   Liquid biopsy  

Oesophageal Squamous Cell Carcinoma (OSCC) is one of the most common malignant tumours globally, with a particularly high incidence in East Asia. Neoadjuvant Chemoradiotherapy (NCRT) is the standard treatment for locally advanced oesophageal cancer, aiming to reduce tumour volume and improve surgical resection rates. However, some patients may achi...

Carbohydrate Antigen 19-9 (CA19-9) Response After Induction FOLFIRINOX for Locally Advanced Pancreatic Cancer Identifies Patients Who May Benefit from Surgical Exploration: Multicentre, Observational Cohort Study

Medicine, Oncology,
Locally Advanced Pancreatic Cancer   CA19-9   FOLFIRINOX   Surgical Exploration   Prognostic Factors   Survival Rate  

Pancreatic cancer is a highly malignant tumor with an extremely low five-year survival rate, especially for patients with locally advanced pancreatic cancer (LAPC), who have limited treatment options and poor prognosis. LAPC is defined based on the degree of tumor contact with adjacent blood vessels and is often considered “unresectable” at diagnos...