Lymphatic Vessel Transit Seeds Cytotoxic Resident Memory T Cells in Skin Draining Lymph Nodes

Lymphatic Vessel Transit Seeds Cytotoxic Resident Memory T Cells in Skin Draining Lymph Nodes

Background Introduction The immune system plays a crucial role in responding to viral infections, and T cell memory is especially important in secondary immune responses. This paper focuses on how resident memory T cells (LN TRMs) in lymph nodes are formed after skin infections. LN TRMs play a key role in immune memory at specific sites, but their ...

Characterization of early inflammatory responses and cytokine changes during schistosome infection

对于一篇关于血吸虫感染早期反应的深入研究,Houlder等人撰写的论文为科学界提供了重要的见解。他们的研究发表于《科学免疫学》(Sci. Immunol.) 2024年7月5日的第9卷,揭示了血吸虫(Schistosoma mansoni...

Cytokines Drive the Formation of Memory-Like NK Cell Subsets via Epigenetic Rewiring and Transcriptional Regulation

Cytokines Drive the Formation of Memory-Like NK Cell Subsets via Epigenetic Rewiring and Transcriptional Regulation

In the context of today’s rapid advancement in science and technology, immunotherapy with natural killer (NK) cells has attracted widespread attention in the scientific community for their potential advantages in combating tumors and viral infections. Especially, the discovery of memory-like NK cells has brought new hope for NK cells as an anticanc...

An Explainable and Personalized Cognitive Reasoning Model Based on Knowledge Graph: Toward Decision Making for General Practice

An Explainable and Personalized Cognitive Reasoning Model Based on Knowledge Graph: Toward Decision Making for General Practice

An Explainable and Personalized Cognitive Reasoning Model Based on Knowledge Graph: Toward Decision Making for General Practice Background General medicine, as an important part of community and family healthcare, covers different ages, genders, organ systems, and various diseases. Its core concept is human-centered, family-based, emphasizing long-...

Gastrointestinal infections and gastrointestinal haemorrhage are underestimated but serious adverse events in chimeric antigen receptor T-cell recipients: a real-world study

Gastrointestinal Infections and Gastrointestinal Bleeding in CAR-T Cell Recipients are Underrated but Severe Adverse Events: A Real-World Study Introduction In recent years, Chimeric Antigen Receptor T-cell (CAR-T) therapy has shown lasting efficacy in treating patients with hematologic malignancies. However, multi-system toxic reactions associated...

Measuring Human Auditory Evoked Fields with a Flexible Multi-Channel OPM-Based MEG System

Measuring Human Auditory Evoked Fields with a Flexible Multi-Channel OPM-Based MEG System

Measurement of Human Auditory Evoked Fields Using a Flexible Multichannel Optically Pumped Magnetometer MEG System Xin Zhang and others, from the Suzhou Institute of Biomedical Engineering and Technology of the Chinese Academy of Sciences, University of Science and Technology of China, Jihua Laboratory in Foshan, Guangdong Province, and Guoke Medic...