Quantitative Integrative Survival Prediction in Multiple Myeloma Patients

Precision Medicine | Quantitative Comprehensive Survival Prediction for Patients with Multiple Myeloma: Based on Bortezomib Induction Therapy, High-Dose Treatment, and Autologous Stem Cell Transplantation Introduction Multiple myeloma is a malignant hematological disease characterized by the accumulation of clonal plasma cells within the bone marro...

Clonal Hematopoiesis in Patients with Neuroendocrine Tumor Treated with Lutetium-177 and the Risk of Thrombocytopenia: A Prospective Study

Clonal Hematopoiesis in Patients with Neuroendocrine Tumor Treated with Lutetium-177 and the Risk of Thrombocytopenia: A Prospective Study

Clonal Hematopoiesis and Risk of Thrombocytopenia in Neuroendocrine Tumor Patients Undergoing 177Lu Therapy: A Prospective Study Background and Research Motivation The incidence of Neuroendocrine Tumors (NETs) has gradually increased in recent years. Prognosis depends on various factors such as the location of the primary tumor, disease grading, st...

Comprehensive Genomic Analysis of Patients with Non–Small-Cell Lung Cancer Using Blood-Based Circulating Tumor DNA Assay: Findings from the BFAST Database of a Single Center in Taiwan

Latest Research in Lung Cancer Genomics: Analysis of Circulating Tumor DNA Detection in Non-Small Cell Lung Cancer Background and Motivation In recent years, the treatment of non-small cell lung cancer (NSCLC) has seen significant changes due to the success of targeted therapies. The National Comprehensive Cancer Network guidelines recommend extens...

Aging-Induced MCPH1 Translocation Activates Necroptosis and Impairs Hematopoietic Stem Cell Function

Study on MCPH1 Nuclear Transfer Induced by Aging Activating Necrosis and Impairing Hematopoietic Stem Cell Function Research Background The aging of hematopoietic stem cells is associated with an increased risk of various blood diseases, and DNA damage is a significant factor driving the aging of hematopoietic stem cells. However, the underlying mo...

Autoimmune Conditions and Gastric Cancer Risk in a Population-Based Study in the United Kingdom

The Relationship Between Autoimmune Diseases and Gastric Cancer Risk in the British Population Background Introduction Despite the overall incidence of gastric cancer has declined over the past few decades, the incidence of gastric cancer among young people in some Western countries has increased in recent years. This trend may be related to the in...

Outdoor Air Pollution and Risk of Incident Adult Haematologic Cancer Subtypes in a Large US Prospective Cohort

A Large Prospective Cohort Study in the United States Reveals Potential Links Between Outdoor Air Pollution and Subtypes of Adult Hematologic Cancers Background and Purpose In recent years, the impact of outdoor air pollution on human health has garnered extensive attention. Since 2013, the International Agency for Research on Cancer (IARC) has cla...