Targeted Drug Delivery Using Self-Unrolling Sheets in Magnetically Actuated Capsules

Targeted Drug Delivery Using Self-Unrolling Sheets in Magnetically Actuated Capsules Background Gastrointestinal (GI) diseases, such as inflammatory bowel disease, GI bleeding, and cancer, are significant global health issues. Traditional treatment methods, such as endoscopy and oral medications, though effective to some extent, have many limitatio...

Residual-Dense Network for Glaucoma Prediction Using Structural Features of Optic Nerve Head

Using Residual Dense Network (RD-Net) for Glaucoma Prediction Based on Structural Features of the Optic Nerve Head Background and Research Purpose Glaucoma is one of the leading causes of blindness worldwide, often referred to as the “silent thief of sight.” It is characterized by the progressive degeneration of the optic nerve head (ONH), resultin...

Single-Molecule Systems for the Detection and Monitoring of Plasma-Circulating Nucleosomes and Oncoproteins in Diffuse Midline Glioma

Exploring the Applications of Single-Molecule Systems for Detection and Monitoring of Plasma-Circulating Nucleosomes and Oncoproteins in Diffuse Midline Glioma Research Background and Problem Overview Diffuse Midline Glioma (DMG) is a highly aggressive brain tumor primarily affecting children with extremely high mortality rates. This type of tumor ...

GLUT1-targeted near-infrared fluorescence molecular imaging for precise intraoperative detection of breast cancer

A Novel GLUT1-Targeted Fluorescence Imaging Tracer: Advances in Intraoperative Breast Cancer Detection Background and Problem Statement Breast cancer is one of the most common malignancies among women worldwide, with an estimated 2.3 million new cases and approximately 666,000 deaths globally in 2022. Surgical treatment for breast cancer typically ...

Fibroblast Activation Protein-Targeted NIR-I/II Fluorescence Imaging for Detecting Hepatocellular Carcinoma

A Novel Near-Infrared Fluorescence Imaging Study Targeting Hepatocellular Carcinoma (HCC) Hepatocellular carcinoma (HCC) ranks as the sixth most common malignancy and the third leading cause of cancer-related mortality worldwide. Statistics indicate that the postoperative recurrence rate of HCC reaches as high as 80%, with liver fibrosis or cirrhos...