Integrative Molecular and Spatial Analysis Reveals Evolutionary Dynamics and Tumor-Immune Interplay of In Situ and Invasive Acral Melanoma

Integrative Molecular and Spatial Analysis Reveals Evolutionary Dynamics and Tumor-Immune Interplay of In Situ and Invasive Acral Melanoma

Medicine, Oncology, Life Sciences, Cell Biology, Immunology, Genetics,
integrative molecular analysis   spatial analysis   acral melanoma   evolutionary dynamics   tumor-immune interplay   early invasion   prognostic biomarker  

Integrated Molecular and Spatial Analysis Reveals Evolutionary Dynamics and Tumor-Immune Interactions in In Situ and Invasive Acral Melanoma Academic Background of the Paper Melanoma is a type of skin cancer, and acral melanoma (AM) is a kind that occurs on non-exposed areas such as the palms, soles, and under the nails and is particularly common a...

Development and Standardization of an Osteoradionecrosis Classification System in Head and Neck Cancer: Implementation of a Risk-Based Model

Medicine, Oncology,
head and neck cancer   osteoradionecrosis   classification system   radiation therapy   risk factors  

Development and Standardization of an Osteoradionecrosis Classification System in Head and Neck Cancer: Implementation Based on Risk Model In recent years, the side effects brought by the treatment of head and neck cancer (HNC), especially radiotherapy, have become a focal point of academic attention. Osteoradionecrosis (ORN) is one of the most sev...

Clinical and Genomic-Based Decision Support System to Define the Optimal Timing of Allogeneic Hematopoietic Stem-Cell Transplantation in Patients with Myelodysplastic Syndromes

Clinical and Genomic-Based Decision Support System to Define the Optimal Timing of Allogeneic Hematopoietic Stem-Cell Transplantation in Patients with Myelodysplastic Syndromes

Medicine, Hematology, Oncology, Life Sciences, Genetics,
Myelodysplastic Syndromes   Allogeneic Hematopoietic Stem-Cell Transplantation   Decision Support System   Clinical and Genomic Information   Prognostic Scoring System   Personalized Therapy  

Background Myelodysplastic Syndromes (MDS) are a group of heterogeneous diseases originating from bone marrow hematopoietic stem cells, characterized by reduced blood cell production. Although certain progress in treatment has been made in recent years, allogeneic hematopoietic stem-cell transplantation (HSCT) remains the only potentially curative ...

Intimate Care Products and Incidence of Hormone-Related Cancers: A Quantitative Bias Analysis

Medicine, Nursing, Environmental and Public Health, Oncology,
Intimate Care Products   Hormone-Related Cancers   Genital Talc   Douching   Recall Bias   Exposure Misclassification   US Cohort Study  

Incidence of Hormone-Related Cancers and Intimate Care Products Introduction In recent years, there has been an increasing concern about the safety of intimate care products that may contain potential endocrine disrupting chemicals, such as phthalates, parabens, and bisphenols. These chemicals are believed to alter endogenous hormone levels, influe...

Feasibility of Electronic Patient-Reported Outcomes in Older Cancer Patients

Medicine, Environmental and Public Health, Oncology,
electronic patient-reported outcomes   older patients   cancer care   remote monitoring   quality of life   technological barriers  

Multicenter Prospective Study: Feasibility of Electronic Patient-Reported Outcomes (ePROs) in Elderly Cancer Patients Research Background In recent years, telemedicine has developed rapidly, especially during the COVID-19 pandemic, and is considered a solution to the problem of medical personnel shortages. Electronic patient-reported outcomes (ePRO...

Safety and Efficacy of Surgical Implantation of Intrathecal Drug Delivery Pumps in Patients With Cancer With Refractory Pain

Medicine, Anesthesiology, Neurosurgery, Oncology,
intrathecal pump   cancer pain   palliative care  

Safety and Efficacy of Intrathecal Drug Delivery Pumps for Intractable Pain in Cancer Patients Introduction Pain management in cancer patients is a critical issue in palliative care, as clinicians strive to improve patients’ quality of life and alleviate their suffering. Most cancer patients experience cancer-related pain, and 30%-40% of them suffe...