Precise Colorectal Cancer Screening Based on Customized Intervals Using Fecal Hemoglobin Concentration Researchers: Amy Ming-Fang Yen, Yang-Ching Chen, Yu-Lin Ding, Wen-Zhu Qiu, Han-Mo Qiu, Tony Hsiu-Hsi Chen, Sam Li-Sheng Chen Academic Background Colorectal cancer (CRC) is the third most prevalent malignancy worldwide. In recent years, significant...
Oncolytic Mineralized Bacteria May Be Used for Tumor Immunotherapy via Local Injection Research Background As a novel cancer treatment method, bacteria-based cancer immunotherapy has a long history dating back to the late 19th century when heated, inactivated bacteria were used to treat sarcomas. Initial trials found that these bacteria could trigg...
Generation of Synthetic Whole-Slide Images of Tumors from RNA Sequencing Data via Cascaded Diffusion Models A recent study published in Nature Biomedical Engineering, titled “Generation of Synthetic Whole-Slide Image Tiles of Tumours from RNA-Sequencing Data via Cascaded Diffusion Models,” has garnered significant attention. This research, conducte...
Background Introduction Cancer of Unknown Primary (CUP) is a type of malignant disease that is confirmed to be metastatic through histopathology but whose primary site cannot be identified using conventional baseline diagnostic methods. CUP presents significant diagnostic and therapeutic challenges in clinical practice and is believed to account fo...
The Effectiveness of Bivalent CAR T-Cell Therapy Targeting EGFR and IL13Rα2 in Treating Recurrent Glioblastoma In recent years, the treatment of recurrent glioblastoma (RGBM) has been continually explored and improved, yet overall survival rates remain less than one year, presenting a significant challenge. The limitations of existing treatments an...
Integrated Molecular and Spatial Analysis Reveals Evolutionary Dynamics and Tumor-Immune Interactions in In Situ and Invasive Acral Melanoma Academic Background of the Paper Melanoma is a type of skin cancer, and acral melanoma (AM) is a kind that occurs on non-exposed areas such as the palms, soles, and under the nails and is particularly common a...