Study on the Apoptosis Induction of Bladder Cancer Stem Cells by Inhibiting Stearoyl-CoA Desaturase

Medicine, Urology, Oncology, Life Sciences, Cell Biology, Biochemistry,
bladder cancer   stearoyl-CoA desaturase   cancer stem cells   lipid metabolism   apoptosis  

Research Background Bladder cancer is a highly prevalent malignant tumor worldwide, ranking as the fourth most common malignancy in men. According to the 2016 report by the National Cancer Center of China (NCCR), bladder cancer ranks sixth in incidence among male malignancies. Despite continuous improvements in medical diagnostic methods and surgic...

Study on the Antitumor Effects and Mechanism of Erianin in Pancreatic Cancer

Medicine, Gastroenterology, Oncology,
pancreatic cancer   erianin   anticancer   signaling pathway   apoptosis  

Progress in Cancer Research: Inhibitory Mechanisms and Effects of Erianin on Pancreatic Cancer Background and Significance of the Study Pancreatic cancer is a malignant tumor of the digestive tract, characterized by inconspicuous early symptoms, high malignancy, and limited efficacy of conventional radiotherapy and chemotherapy, leading to a very h...

MGA Deletion Leads to Richter’s Transformation by Modulating Mitochondrial OXPHOS

Medicine, Basic Medical Sciences, Hematology, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology,
MGA   Richter's transformation   mitochondria   OXPHOS   CLL  

MGA Deletion Promotes Richter’s Transformation by Regulating Mitochondrial Oxidative Phosphorylation This article mainly focuses on the transformation of chronic lymphocytic leukemia (CLL) into aggressive lymphoma, known as Richter’s Transformation (RT), exploring the function and molecular mechanism of MGA (MAX Gene Associated). MGA is a functiona...

Neural Landscape is Associated with Functional Outcomes in Irradiated Patients with Oropharyngeal Squamous Cell Carcinoma

Medicine, Oral Sciences, Neurology, Neurosurgery, Medical Imaging, Oncology, Life Sciences, Immunology,
Neural landscape   Radiation therapy   Oropharyngeal squamous cell carcinoma   Dysphagia   Neuronal changes   Quality improvement   Functional outcomes  

Research on the Association between Neural Networks and Functional Outcomes in Radiotherapy Patients with Pharyngeal Cancer 1. Paper Background Introduction The incidence of human papillomavirus (HPV)-mediated oropharyngeal squamous cell carcinoma (OPSCC) has significantly increased over the past 40 years, especially among younger populations with ...

Auto-Segmentation of Neck Nodal Metastases Using Self-Distilled Masked Image Transformer on Longitudinal MR Images

Auto-Segmentation of Neck Nodal Metastases Using Self-Distilled Masked Image Transformer on Longitudinal MR Images

Information Science, Artificial Intelligence, Medicine, Medical Imaging, Oncology,
deep learning   convolutional neural network   neck nodal metastases   auto-segmentation   self-supervised learning   vision transformers  

Potential of Self-Distilling Masked Image Transformer in Longitudinal MRI - Automatic Segmentation of Cervical Lymph Node Metastases Report Introduction In tumor radiotherapy, automatic segmentation technology promises to improve speed and reduce inter-reader variability caused by manual segmentation. In radiotherapy clinical practice, accurate and...

Proteomic Stratification of Prognosis and Treatment Options for Small Cell Lung Cancer

Medicine, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology,
small cell lung cancer   proteomics   prognosis   chemotherapy response   immunotherapy  

Proteomic Subtyping of Small Cell Lung Cancer: Analysis of Prognosis and Treatment Strategies Research Background Small Cell Lung Cancer (SCLC) is a highly malignant and heterogeneous cancer characterized by rapid growth, early metastasis, and drug resistance, which limits treatment options and challenges prognostic prediction models. Current genom...