Comparative Efficacy of Balanced Crystalloids versus 0.9% Saline on Delayed Graft Function and Perioperative Outcomes in Kidney Transplantation: A Meta-Analysis of Randomised Controlled Trials

Comparative Efficacy of Balanced Crystalloids versus 0.9% Saline on Delayed Graft Function and Perioperative Outcomes in Kidney Transplantation: A Meta-Analysis of Randomised Controlled Trials Academic Background Kidney transplantation is an effective treatment for end-stage renal disease (ESRD), but delayed graft function (DGF) post-transplantatio...

The Effect of High Protein Dosing in Critically Ill Patients: An Exploratory, Secondary Bayesian Analyses of the EFFORT Protein Trial

The Effect of High Protein Dosing in Critically Ill Patients: An Exploratory, Secondary Bayesian Analysis of the EFFORT Protein Trial Academic Background In the field of critical care medicine, nutritional support is a crucial component of treating critically ill patients. Protein, as a fundamental requirement for cellular function and survival, pl...

Perioperative Fluid Management: Evidence-Based Consensus Recommendations

Perioperative Fluid Management: Evidence-Based Consensus Recommendations from the International Multidisciplinary Perioperative Quality Initiative Academic Background Perioperative fluid management is a critical component of surgical patient care, directly impacting postoperative recovery and complication rates. In recent years, with the continuous...

Human Dorsal Root Ganglia are Either Preserved or Completely Lost After Deafferentation by Brachial Plexus Injury

Paper Title: Human Dorsal Root Ganglia Are Either Preserved or Completely Lost After Deafferentation by Brachial Plexus Injury Authors: Annemarie Sodmann, Johannes Degenbeck, Annemarie Aue, Magnus Schindehütte, Felicitas Schlott, Panagiota Arampatzi, Thorsten Bischler, Max Schneider, Alexander Brack, Camelia M. Monoranu, Tom Gräfenhan, Michael Bohn...

Feasibility of Ultrasound-Guided Nerve Blocks in Simulated Microgravity: A Proof-of-Concept Study for Regional Anaesthesia During Deep Space Missions

Feasibility of Ultrasound-Guided Nerve Blocks in Simulated Microgravity: A Proof-of-Concept Study for Regional Anaesthesia During Deep Space Missions Academic Background With crewed deep space exploration on the horizon, preparing for potential astronaut health crises during space missions has become a critical issue. The administration of anaesthe...

A Two-Person Verbal Check to Confirm Tracheal Intubation: Evaluation of Practice Changes to Prevent Unrecognised Oesophageal Intubation

Background Tracheal intubation is a critical procedure in anesthesia and intensive care. However, despite international campaigns emphasizing the use of capnography to confirm tracheal intubation, unrecognized esophageal intubation continues to result in patient deaths. Esophageal intubation is an avoidable and potentially fatal complication, espec...

International Multi-Institutional External Validation of Preoperative Risk Scores for 30-Day In-Hospital Mortality in Paediatric Patients

External Validation of Preoperative Risk Scores for 30-Day In-Hospital Mortality in Pediatric Patients Academic Background Although the perioperative mortality rate in pediatric patients is low (<0.5%), it remains a significant issue in clinical practice. Traditional risk assessment tools, such as the American Society of Anesthesiologists (ASA) Phy...

Effect of Perioperative Blood Transfusion on Preoperative Haemoglobin Levels as a Risk Factor for Long-Term Outcomes in Patients Undergoing Major Noncardiac Surgery: A Prospective Multicentre Observational Study

Academic Background Preoperative anemia and red blood cell (RBC) transfusions are closely associated with poorer surgical outcomes. Although RBC transfusions can increase oxygen delivery, they are also linked to an increased risk of infectious complications, thromboembolic events, pneumonia, sepsis, cardiac events, and mortality. Therefore, when st...

Risk Model–Guided Clinical Decision Support for Suicide Screening: A Randomized Clinical Trial

Clinical Decision Support Guided by Risk Models in Suicide Screening: A Randomized Clinical Trial Academic Background Suicide prevention is a crucial topic in global public health, particularly in healthcare environments where identifying and intervening in suicide risks are top priorities. Traditional methods for identifying suicide risks rely mai...

Trends in Screening for Social Risk in US Physician Practices

Trends in Screening for Social Risk in US Physician Practices Report Academic Background In recent years, the importance of social risk screening in healthcare has become increasingly prominent, with more research focusing on identifying patients’ social risk factors such as food insecurity, housing instability, utility needs, interpersonal violenc...