Retention of UC-II® Undenatured Type II Collagen During Functional Food and Beverage Prototype Processing

UC-II® Undenatured Type II Collagen Retention in Functional Food and Beverage Processing Academic Background Collagen is widely used in the food and beverage industry to enhance the nutritional and health value of products. Specifically, undenatured type II collagen (UC-II®) has garnered attention for its potential benefits to joint health. However...

Causal Associations Between Sleep Traits, Sleep Disorders, and Glioblastoma: A Two-Sample Bidirectional Mendelian Randomization Study

Causal Associations Between Sleep Traits, Sleep Disorders, and Glioblastoma: A Two-Sample Bidirectional Mendelian Randomization Study Academic Background Introduction Glioblastoma (GBM) is the most aggressive and common type of malignant brain tumor, accounting for nearly 50% of all primary brain tumors in adults. It primarily originates from astro...

The Calcium Channel Blocker Nimodipine Inhibits Spinal Reflex Pathways in Humans

The Effect of Calcium Channel Blocker Nimodipine on Human Spinal Reflex Pathways Academic Background Motor control is one of the essential functions of the nervous system, and spinal reflex pathways play a key role in this process. In animal studies, voltage-sensitive calcium channels (VSCCs) have been identified as critical factors in regulating t...

A Cross-Tissue Transcriptome-Wide Association Study Identifies New Susceptibility Genes for Insomnia

A Cross-Tissue Transcriptome-Wide Association Study Identifies New Susceptibility Genes for Insomnia Background Insomnia is the second most prevalent psychiatric disorder, affecting nearly one-third of the global population. It not only diminishes quality of life but also increases the risk of cardiovascular diseases, metabolic disorders, mood diso...

Transspinal Stimulation Downregulates Flexion Reflex Pathways During Walking in Healthy Humans

Transspinal Stimulation Downregulates Flexion Reflex Pathways During Walking in Healthy Humans Academic Background Human walking is a complex motor process involving the coordinated work of the central and peripheral nervous systems. The spinal cord, as a crucial part of the central nervous system, plays a key role in controlling motor reflexes and...

Control of Movement: Kinematic Hand Synergies Differ Between Reach-and-Grasp and Functional Object Manipulation

Human Hand Movement Control—Differences in Kinematics Between Functional Object Manipulation and Grasping Actions Academic Background The functionality of the human hand plays a crucial role in daily life, particularly through its dexterity, which allows us to use tools to complete various complex tasks. However, millions of people lose hand functi...

The Serotonergic Psychedelic DOI Impairs Deviance Detection in the Auditory Cortex

The Impairment of Deviant Detection in the Auditory Cortex by the Serotonergic Psychedelic DOI Research Background Psychedelics are a class of psychoactive substances capable of significantly altering perception, cognition, and mood. They have recently regained attention due to their potential therapeutic value, such as in treating depression and a...

How Does Orientation-Tuned Normalization Spread Across the Visual Field?

Study on Orientation-Tuned Gain Control Mechanisms in the Visual Cortex Academic Background Visual perception is a complex neural process influenced by contextual environments. Surround suppression is an important phenomenon that describes how the perceived contrast of a stimulus is attenuated when surrounded by other stimuli. The neural mechanisms...

Not Fleeting but Lasting: Limited Influence of Aging on Implicit Adaptive Motor Learning and its Short-Term Retention

The Impact of Aging on Implicit Motor Learning and Short-term Memory: A Study Based on Force Field Adaptation Research Background Motor adaptation is the process by which the brain adjusts motor strategies in response to environmental changes, typically involving two mechanisms: explicit learning and implicit learning. Explicit learning is a rapid,...

Probing Sensorimotor Memory through the Human Speech-Audiomotor System

Research Background Human sensorimotor learning and memory mechanisms have long been a research focus in the field of neuroscience. Most related studies have concentrated on the visuospatial workspace and limb movements, such as arm movements and grasping actions. These studies have helped scientists understand how sensorimotor memories are formed,...