Spatiotemporal Imprinting of Tissue-Resident Memory CD8 T Cell Diversity Background Tissue-resident memory CD8 T cells (TRM cells) provide long-term immune protection at barrier sites such as the intestine. However, the heterogeneity of TRM cells and the mechanisms underlying their formation remain incompletely understood. Previous studies have ide...
Background Introduction In recent years, the discovery of superconductivity in twisted bilayer and trilayer graphene has sparked widespread interest. The key feature of these systems lies in the interplay between interlayer coupling and moiré superlattices, which gives rise to low-energy flat bands with strong correlations. Similar flat bands can a...
Study on Chorus Waves and Field-Particle Energy Transfer in Space Academic Background Chorus waves are among the strongest naturally occurring electromagnetic emissions, widely observed in the magnetospheres of Earth and other planets. These waves not only pose radiation hazards to satellites and astronauts but also play a crucial role in accelerat...
Global 3D Model of Mantle Attenuation: A Study Based on Seismic Normal Modes Academic Background The structure and dynamic processes of Earth’s interior have always been at the core of geoscientific research. Mantle convection is the primary mechanism driving plate tectonics, volcanic eruptions, and earthquakes. However, traditional seismic tomogra...
The Impact of the Maternal X Chromosome on Cognition and Brain Aging in Female Mice Background Introduction In mammals, female cells possess two X chromosomes, one from the mother (maternal X chromosome, Xm) and one from the father (paternal X chromosome, Xp). During embryonic development, one of the X chromosomes is randomly inactivated, a process...
The Key Role of RELMβ in Food Allergy Academic Background Food allergy (FA) is a common immune system disorder, particularly prevalent among children. The occurrence of food allergy is associated with abnormal immune responses to food antigens, especially the dysregulation of type 2 immune responses. Type 2 immune responses are typically defense me...
Research on the Functional Mapping of Rubisco Enzyme Background Introduction Rubisco (ribulose-1,5-bisphosphate carboxylase/oxygenase) is the most abundant enzyme on Earth, responsible for the carbon dioxide fixation process in photosynthesis. However, Rubisco’s catalytic efficiency is low, and it is prone to side reactions with oxygen, limiting th...
Mitochondrial Transfer and Immune Evasion Mechanisms in the Tumor Microenvironment Academic Background Tumor cells evade immune system attacks, particularly by T cells, through various mechanisms in the Tumor Microenvironment (TME). Although Immune Checkpoint Inhibitors (ICIs) have achieved significant progress in the treatment of various cancers, ...
Complete Human Recombination Maps Academic Background In genetic research, recombination is one of the key mechanisms by which organisms generate genetic diversity. Recombination not only affects the transmission and combination of genes but also plays a crucial role in natural selection and population history inference. However, existing recombina...
Precise Modeling of Mitochondrial Diseases: Research Based on Optimized Mitobes Academic Background Mitochondrial diseases are a group of genetic disorders caused by mutations in mitochondrial DNA (mtDNA), which affect cellular energy metabolism and lead to dysfunction in multiple organs. Mitochondrial DNA mutations can be homoplasmic (affecting al...