A Spectroscopic Method for Distinguishing Two Novel Sandwich-Type Tungsten Oxide Cluster Compounds

Distinguishing Novel Sandwich-Type Tungsten Oxide Cluster Compounds Using Two-Dimensional Correlation Infrared Spectroscopy Background Introduction Polyoxometalates (POMs) are metal-oxygen cluster compounds linked through oxygen coordination with transition metal ions. They play significant roles in catalysis, optics, medicine, and magnetism. Howev...

Ion-Concentration-Dependent Dynamic Mechanism of Thiolactic-Acid-Capped Gold Nanoclusters Revealed by Fluorescence Spectra and Two-Dimensional Correlation Spectroscopy

Background and Research Questions Atomic gold nanoclusters (AuNCs), with particle sizes typically not exceeding 2 nanometers, have garnered extensive attention in recent years due to their unique photophysical properties, making them highly advantageous in biomedicine, catalysis, and sensing. These properties include excellent catalytic activity, t...

Surface Structural Changes in Silicone Rubber Due to Electrical Tracking

Cutting-Edge Scientific News: Research Reveals Degradation Mechanisms of Silicone Rubber under Electrical Tracking Background: Motivation and Challenges With the rapid development of power transmission and distribution systems, polymer composite insulators have gradually replaced traditional glass and ceramic insulators as the preferred materials f...

Development of Next Generation Low-Cost OCT Towards Improved Point-of-Care Retinal Imaging

Development of Next-Generation Low-Cost Optical Coherence Tomography (OCT) Systems: Advancing Retinal Imaging for Clinical Applications Academic Background Optical Coherence Tomography (OCT) is a non-invasive, high-resolution imaging technology widely used in ophthalmology, particularly for diagnosing retinal diseases. However, existing commercial ...

Spatial Multiomic Landscape of the Human Placenta at Molecular Resolution

A New Chapter in the Molecular Understanding of the Human Placenta: Breakthroughs in Spatial Multiomics Background and Research Questions The placenta is the first fetal organ to develop during human pregnancy and plays a critical role in ensuring successful gestation and healthy fetal development. Despite its importance, our understanding of the m...

Gene-Level Alignment of Single-Cell Trajectories

Gene-level Single-cell Trajectory Alignment: A New Method Based on Dynamic Programming The advent of single-cell RNA sequencing (scRNA-seq) technology has dramatically advanced biological research, enabling scientists to observe dynamic changes at the single-cell level over time and space. However, comparing such dynamics across samples or conditio...

Single-cell and spatially resolved interactomics of tooth-associated keratinocytes in periodontitis

Single-Cell and Spatially Resolved Interactomics of Tooth-Associated Keratinocytes: Exploring the Role of Structural Immunity in Periodontitis Background Periodontitis is a chronic inflammatory disease that affects the periodontal tissues and impacts billions of people globally, potentially resulting in tooth loss. It is primarily caused by polybac...

Super-Resolution Imaging of Fast Morphological Dynamics of Neurons in Behaving Animals

Super-Resolution Imaging Reveals New Advances in Neural Morphodynamics in Mouse Brains: Dynamic Observations in Head-Fixed Awake Animals Background In the field of neuroscience, understanding the morphological changes and functional dynamics of neurons is key to deciphering how the brain processes information and sustains network plasticity. Despit...

An Organotypic Atlas of Human Vascular Cells

Decoding the Human Vascular System: A Comprehensive Multi-organ Single-cell Transcriptomic Study Reveals Vascular Cell Diversity Background Overview The human vascular system is a core component for sustaining life, comprising endothelial cells (ECs) and mural cells that span across all organ systems. Its functions extend beyond merely delivering b...

A Temporal Cortex Cell Atlas Highlights Gene Expression Dynamics During Human Brain Maturation

Gene Expression Dynamics During Human Brain Maturation: A Novel Temporal Cortex Cell Atlas Academic Background The development and maturation of the human brain are critical areas in neuroscience, though many mysteries remain unresolved. Guided by changes in gene expression, the human brain undergoes a prolonged and complex postnatal maturation pro...