Histone Lactylation-Mediated Overexpression of RASD2 Promotes Endometriosis Progression via Upregulating the SUMOylation of CTPS1

Medicine, Obstetrics and Gynecology,
Histone Lactylation   Endometriosis   RASD2   CTPS1   SUMOylation  

Histone Lactylation Promotes Endometriosis Progression by Upregulating CTPS1 SUMOylation Academic Background Endometriosis is a common reproductive endocrine disease affecting approximately 10% of women of reproductive age worldwide. Its main symptoms include dysmenorrhea, chronic pelvic pain, infertility, and menstrual abnormalities. Although the ...

The Runx2-NLRP3 Axis Orchestrates Matrix Stiffness-Evoked Vascular Smooth Muscle Cell Inflammation

Medicine, Nephrology, Cardiovascular System, Life Sciences, Immunology,
chronic kidney disease   matrix stiffness   NLRP3   Runx2   vascular smooth muscle cell inflammatory phenotype  

Chronic Kidney Disease: Runx2-NLRP3 Axis Regulates Matrix Stiffness-Induced Vascular Smooth Muscle Cell Inflammation Academic Background Chronic Kidney Disease (CKD) is a common condition worldwide, leading to high morbidity and mortality rates among patients and significantly increasing the risk of cardiovascular events. Arterial stiffening, chara...

Conformal Depression Prediction

Information Science, Artificial Intelligence, Medicine, Psychiatry, Clinical Psychology,
Depression Prediction   Uncertainty Quantification   Conformal Prediction   Approximate Conditional Coverage   Facial Depression Prediction  

Research on Depression Prediction Method Based on Conformal Prediction Background Introduction Depression is a common mental disorder characterized by persistent sadness, debilitation, and loss of interest in activities. It not only increases the risk of suicide but also imposes a significant psychological burden on patients and their families. Cur...

Assessment of Distraction and the Impact on Technology Acceptance of Robot Monitoring Behaviour in Older Adults Care

Information Science, Automation, Artificial Intelligence, Medicine, Geriatrics, Clinical Psychology,
distraction   technology acceptance   robot monitoring   older adults care   emotional reactions  

The Impact of Robot Monitoring Behavior on Distraction and Technology Acceptance in Older Adults Academic Background With the intensification of societal aging, the demand for elderly care is increasing. Especially during the COVID-19 pandemic, psychological and physiological health issues faced by older adults due to social isolation have become m...

Functional Connectivity Analysis of Children with Autism Under Emotional Clips

Medicine, Psychiatry, Neurology, Clinical Psychology,
Autism Spectrum Disorder   functional connectivity   EEG   emotional processing   classification  

Functional Connectivity Analysis of Children with Autism under Emotional Stimulation Background Introduction Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder, primarily characterized by deficits in social interaction and communication abilities, as well as repetitive behaviors and restricted interests. One of the core feature...

Theory of Mind Abilities Predict Robot’s Gaze Effects on Object Preference

Information Science, Computer Science, Artificial Intelligence, Medicine, Clinical Psychology,
Theory of Mind   robot gaze   object preference   social robotics   cognitive mechanisms  

Academic Background In human social interactions, gaze is one of the most important ways to convey information. Research has shown that human gaze can influence others’ attention, cognition, and even preferences. For example, when a person looks at an object, the observer tends to believe that the object is attractive to the gazer, which in turn in...