Psychological Intervention for Caregivers of Patients with Primary Malignant Brain Tumors

Medicine, Psychiatry, Clinical Psychology, Oncology,
psychological intervention   primary malignant brain tumors   caregivers   anxiety   depression   self-efficacy   coping skills  

Academic Background Caregivers of patients with Primary Malignant Brain Tumors (PMBT) face significant psychological distress. PMBT is not only an incurable cancer but also accompanied by degenerative neurological conditions, leading caregivers to cope with the gradual loss of the patient’s physical functions and irreversible changes in personality...

Efficacy of Cediranib and Olaparib Combination in Platinum-Resistant or Primary Platinum-Refractory Ovarian Cancer

Medicine, Obstetrics and Gynecology, Oncology,
Platinum-resistant ovarian cancer   Cediranib   Olaparib   Combination therapy   Clinical trial  

Academic Background and Problem Statement Epithelial Ovarian Cancer (EOC) remains one of the leading causes of death among gynecologic malignancies. Although the incorporation of molecularly targeted therapies, such as bevacizumab and PARP inhibitors, has improved Progression-Free Survival (PFS) and, in some cases, Overall Survival (OS), many patie...

Inotuzumab Ozogamicin and Low-Intensity Chemotherapy in Older Patients with Newly Diagnosed CD22+ Philadelphia Chromosome–Negative B-Cell Precursor Acute Lymphoblastic Leukemia

Medicine, Hematology, Oncology,
Inotuzumab Ozogamicin   Low-Intensity Chemotherapy   Acute Lymphoblastic Leukemia   Older Patients   CD22 Positive   Philadelphia Chromosome Negative   B-Cell Precursor  

Academic Background and Problem Acute lymphoblastic leukemia (ALL) is a malignant hematologic disease, particularly challenging to treat in older patients, with limited treatment options and poor outcomes. Traditional chemotherapy regimens yield long-term survival rates of only 20%-30% in elderly patients. Therefore, finding more effective and bett...

Impact of Adjuvant Chemotherapy on Resected Intraductal Papillary Mucinous Neoplasm-Derived Pancreatic Cancer: Results from an International Multicenter Study

Medicine, Oncology,
Pancreatic Cancer   Intraductal Papillary Mucinous Neoplasm   Adjuvant Chemotherapy   Survival Analysis   International Multicenter Study  

Impact of Adjuvant Chemotherapy on Resected Intraductal Papillary Mucinous Neoplasm-Derived Pancreatic Cancer: Results from an International Multicenter Study Academic Background Intraductal Papillary Mucinous Neoplasm (IPMN) is the most common type of pancreatic cyst, and its incidence and prevalence have been increasing due to the widespread use ...

Delivering High-Quality Cancer Care: One Decade Later

Medicine, Oncology,
cancer care   high-quality care   patient engagement   health policy   care models  

Delivering High-Quality Cancer Care: A Decade Later Academic Background In 2012, the National Academies of Sciences, Engineering, and Medicine (NASEM) convened a committee to address the quality of cancer care in the United States and provide recommendations to policymakers and the cancer care community on strategies to improve cancer care delivery...

PEARL: A Phase Ib/II Biomarker Study of Adding Radiation Therapy to Pembrolizumab Before Neoadjuvant Chemotherapy in HER2-Negative Breast Cancer

Medicine, Oncology, Life Sciences, Immunology,
breast cancer   radiation therapy   Pembrolizumab   neoadjuvant chemotherapy   biomarkers   HER2-negative   tumor-infiltrating lymphocytes  

Academic Background Breast cancer is one of the most common cancers among women worldwide, particularly triple-negative breast cancer (TNBC) and hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) breast cancer, which are known for their aggressive nature and poor prognosis. In recent years, immune checkpoint inh...