The Role of lncRNA-Mediated ceRNA Network in Penile Squamous Cell Carcinoma

Medicine, Urology, Oncology, Life Sciences, Immunology, Genetics,
long non-coding RNA   competing endogenous RNA network   penile squamous cell carcinoma   tumor microenvironment   immunosuppression  

The Role of lncRNA-Mediated ceRNA Network in Penile Squamous Cell Carcinoma Academic Background Penile Squamous Cell Carcinoma (PSCC) is a relatively rare but life-threatening malignancy that poses a significant health risk to men, particularly in developing countries. Despite advancements in medical diagnosis and treatment, the overall survival ra...

Combined Single Cell and Spatial Transcriptome Analysis Reveals Cellular Heterogeneity of Hedgehog Pathway in Gastric Cancer

Medicine, Gastroenterology, Oncology, Life Sciences, Cell Biology, Immunology, Genetics,
Gastric Cancer   Hedgehog Pathway   Single-Cell Sequencing   Spatial Transcriptomics   Tumor Microenvironment   CCND1   Fibroblasts  

Combined Single-Cell and Spatial Transcriptome Analysis Reveals Cellular Heterogeneity of the Hedgehog Pathway in Gastric Cancer Academic Background Gastric cancer (GC) is one of the most common and deadly malignancies worldwide, with high incidence and mortality rates. Despite advancements in chemotherapy, radiotherapy, and targeted therapy, the t...

Neoantigen-Specific mRNA/DC Vaccines for Effective Anticancer Immunotherapy

Medicine, Oncology, Life Sciences, Immunology,
neoantigen   mRNA vaccine   dendritic cells   anticancer immunotherapy   personalized treatment  

Effectiveness of Neoantigen-Specific mRNA/DC Vaccines in Anticancer Immunotherapy Academic Background Cancer immunotherapy has emerged as a significant breakthrough in cancer treatment in recent years. Among the various approaches, dendritic cell (DC) vaccines have shown potential in extending the survival of some advanced cancer patients. However,...

MALDI Imaging Combined with Two-Photon Microscopy Reveals Local Differences in the Heterogeneity of Colorectal Cancer

MALDI Imaging Combined with Two-Photon Microscopy Reveals Local Differences in the Heterogeneity of Colorectal Cancer

Medicine, Medical Laboratory Science, Medical Imaging, Oncology,
colorectal cancer   tumor microenvironment   collagen fibers   two-photon microscopy   MALDI imaging   proteomics   heterogeneity  

Multimodal Imaging Study of the Tumor Microenvironment in Colorectal Cancer: Revealing Spatial Heterogeneity Academic Background Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide, with its complexity and heterogeneity posing significant challenges for treatment and prognosis prediction. The tumor microe...

Rapid Full-Color Serial Sectioning Tomography with Speckle Illumination and Ultraviolet Excitation

Rapid Full-Color Serial Sectioning Tomography with Speckle Illumination and Ultraviolet Excitation

Medicine, Medical Laboratory Science, Medical Imaging, Oncology, Life Sciences, Bioengineering,
tomography   full-color imaging   biological tissue   high-resolution   optical sectioning  

Academic Background Three-dimensional (3D) high-resolution large-volume imaging has remained a significant challenge in the field of biomedical research. Traditional two-dimensional (2D) slice imaging, while capable of providing planar morphological information of tissues and cells, fails to comprehensively display internal 3D structural informatio...

Impact of Dietary Zinc on Stimulated Zinc Secretion MRI in the Healthy and Malignant Mouse Prostate

Medicine, Urology, Medical Imaging, Oncology,
Dietary Zinc   Prostate Cancer   MRI Imaging   Zinc Secretion   Mouse Model  

Impact of Dietary Zinc on Stimulated Zinc Secretion MRI in the Healthy and Malignant Mouse Prostate Academic Background Zinc (Zn²⁺) is an essential trace element in biological systems, participating in various physiological processes, including enzyme catalysis, structural regulation of transcription factors, immune system modulation, and cell prol...