Clinical Analysis of MOG Antibody-Associated Disease Overlapped with Anti-NMDA Receptor Encephalitis: A Long-Term Retrospective Study

Medicine, Neurology, Life Sciences, Immunology,
MOG antibody-associated disease   anti-NMDA receptor encephalitis   overlapping syndrome   clinical characteristics   radiological features   treatment   prognosis  

Clinical Analysis of MOG Antibody-Associated Disease Overlapping with Anti-NMDAR Encephalitis Background In recent years, with the in-depth study of autoimmune encephalitis (AE) and demyelinating diseases of the central nervous system (CNS), scientists have identified some rare cases of overlapping syndromes. Among them, the overlap between MOG Ant...

Periodic and Aperiodic Components of Subthalamic Nucleus Activity Reflect Different Aspects of Motor Impairment in Parkinson's Disease

Medicine, Neurology,
Parkinson's disease   subthalamic nucleus   motor impairment   periodic activity   aperiodic activity   deep brain stimulation   levodopa  

Periodic and Aperiodic Components of Subthalamic Nucleus Activity Reflect Different Aspects of Motor Impairment in Parkinson’s Disease Background Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by core symptoms such as bradykinesia, rigidity, and tremor. Although the neurophysiology of PD has been extensively studied, ...

Oscillatory Transcranial Electrical Stimulation and the Amplitude-Modulated Frequency Dictate the Quantitative Features of Phosphenes

Medicine, Neurology, Ophthalmology, Life Sciences, Biophysics,
transcranial electrical stimulation   phosphene   amplitude modulation frequency   oscillatory current   visual perception  

Oscillatory Transcranial Electrical Stimulation and the Quantitative Features of Phosphene Perception Background Introduction Phosphenes refer to the phenomenon of perceiving light points without any external visual stimuli. This phenomenon holds significant importance in visual neuroscience and consciousness studies, as it helps us understand how ...

Resting State Functional Connectivity of the Default Mode Network During Opioid Use and Cessation in Treatment-Seeking Persons

Medicine, Psychiatry, Neurology, Medical Imaging,
resting-state functional connectivity   default mode network   opioid use disorder   withdrawal symptoms   neuroimaging   addiction mechanisms   relapse prediction  

Functional Connectivity of the Default Mode Network During Opioid Use and Cessation Background Opioid abuse has become a global public health issue, particularly in the United States, where opioid overdose deaths have tripled since 1999. Opioids not only lead to addiction but are also associated with chronic pain, immune system suppression, and neu...

Oxyglutamate Carrier Alleviates Cerebral Ischaemia–Reperfusion Injury by Regulating Mitochondrial Function

Medicine, Neurology, Life Sciences,
cerebral ischaemia–reperfusion injury   mitochondrial function   neuron   oxyglutamate carrier   reactive oxygen species  

The Role of Oxyglutamate Carrier in Cerebral Ischemia-Reperfusion Injury Academic Background Cerebral ischemia-reperfusion injury (I/R) is a significant issue in the treatment of ischemic stroke. Although rapid blood flow restoration through thrombectomy and intravenous rt-PA (recombinant tissue plasminogen activator) administration can effectively...

Subtype-Specific Differences in Metabolic Profiles of Pancreatic Cancer Tumor Organoids

Medicine, Oncology, Life Sciences, Biochemistry,
Pancreatic cancer   Metabolic reprogramming   Glycolysis   Oxidative phosphorylation   Tumor organoids   Subtype-specific   Mitochondrial pyruvate carrier  

Metabolic Characteristics of Pancreatic Ductal Adenocarcinoma (PDAC) Subtypes Background Pancreatic Ductal Adenocarcinoma (PDAC) is a highly aggressive cancer with a five-year survival rate of only 13%, making it the third leading cause of cancer-related deaths. The aggressiveness and chemoresistance of PDAC are closely linked to its complex metabo...