Cortical Morphological Networks Differ Between Gyri and Sulci

Differences in Brain Cortical Morphological Networks Between Gyri and Sulci Introduction The human brain, as an interconnected complex network, can be mapped through virtual imaging using multimodal magnetic resonance imaging (MRI) technology. By analyzing this network using graph theory methods, many studies have discovered some non-trivial topolo...

Fluoxetine Rescues Excessive Myelin Formation and Psychological Behaviors in a Murine PTSD Model

Fluoxetine Rescues Excessive Myelin Formation and Psychological Behaviors in a Murine PTSD Model Background Post-traumatic stress disorder (PTSD) is a complex mental disorder characterized by spontaneous intrusions of traumatic memories, avoidance of trauma-related stimuli, negative emotions and cognitions, and hyperarousal. Although existing first...

Serum LDL Promotes Microglial Activation and Exacerbates Demyelinating Injury in Neuromyelitis Optica Spectrum Disorder

Study on Serum LDL Promoting Microglial Activation and Exacerbating Demyelination in Neuromyelitis Optica Spectrum Disorder Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune inflammatory demyelinating disease of the central nervous system (CNS), often accompanied by disruption of the blood-brain barrier (BBB). Dysfunction of lipid met...

Nucleus Accumbens Corticotropin-Releasing Hormone Neurons Projecting to the Bed Nucleus of the Stria Terminalis Promote Wakefulness and Positive Affective State

Nucleus Accumbens Corticotropin-Releasing Hormone Neurons Project to Bed Nucleus of the Stria Terminalis to Regulate Wakefulness and Positive Emotional States Background The nucleus accumbens (NAc) plays a crucial role in regulating motivation, reward, and many behaviors that depend on high levels of arousal. However, research on the neural mechani...

Low-Frequency Stimulation at the Subiculum Prevents Extensive Secondary Epileptogenesis in Temporal Lobe Epilepsy

In the field of neuroscience, epilepsy has always been a disease of great concern, with significant challenges remaining in clinical research and treatment. Among these, the issue of secondary epileptogenesis has had a profound impact on academia and clinical treatment. Secondary epileptogenesis refers to the continuous spread of epileptic activity...

The Role of Occipitotemporal Network for Speed-Reading: An fMRI Study

The Role of Occipitotemporal Network for Speed-Reading: An fMRI Study

The Role of Occipitotemporal Network in Rapid Reading - An fMRI-based Study Background Reading is the most effective cognitive means for humans to acquire new knowledge. Although most native English-speaking adults read at an average speed of about 200 to 400 words per minute (w/min), many people hope to increase their reading speed to acquire new ...