Impact of an Epstein-Barr Virus Serology-Based Screening Program on Nasopharyngeal Carcinoma Mortality: A Cluster-Randomized Controlled Trial

Medicine, Infectious Diseases, Oncology,
Nasopharyngeal carcinoma   Epstein-Barr virus   Screening   Mortality   Cluster-randomized controlled trial  

Impact of an Epstein-Barr Virus Serology-Based Screening Program on Nasopharyngeal Carcinoma Mortality: A Cluster-Randomized Controlled Trial Academic Background Nasopharyngeal carcinoma (NPC) is a malignant tumor that is highly prevalent in Asia, particularly in southern China. Approximately 85% of NPC cases occur in Asia, with the incidence being...

Fiber Optics-Based Surface Enhanced Raman Spectroscopy Sensors for Rapid Multiplex Detection of Foodborne Pathogens in Raw Poultry

Chemistry, Analytical Chemistry, Engineering, Electrical Engineering, Medicine, Infectious Diseases, Life Sciences, Bioengineering, Microbiology,
Surface Enhanced Raman Spectroscopy   Foodborne Pathogens   Raw Poultry   Multiplex Detection   Fiber Optics Sensor   Rapid Detection   Food Safety  

Fiber Optics-Based Surface Enhanced Raman Spectroscopy Sensors for Rapid Multiplex Detection of Foodborne Pathogens in Raw Poultry Academic Background Foodborne illnesses are a significant global public health challenge, with Salmonella being one of the leading pathogens causing such diseases. In the United States alone, Salmonella results in 1.35 ...

The Respiratory Microbiome is Linked to the Severity of RSV Infections and the Persistence of Symptoms in Children

Medicine, Infectious Diseases, Pediatrics, Respiratory System, Life Sciences, Microbiology,
respiratory microbiome   RSV infection   symptom persistence   child health   microbial community  

The Respiratory Microbiome is Linked to the Severity of RSV Infections and the Persistence of Symptoms in Children Academic Background Respiratory Syncytial Virus (RSV) is a leading cause of respiratory infections and hospitalizations in infants. While known risk factors for severe infections include preterm birth, congenital heart disease, and bro...

Ongoing Evolution of SARS-CoV-2 Drives Escape from mRNA Vaccine-Induced Humoral Immunity

Medicine, Infectious Diseases, Life Sciences, Immunology, Microbiology,
SARS-CoV-2   mRNA vaccine   humoral immunity   viral mutation   neutralizing antibodies  

The Ongoing Evolution of SARS-CoV-2 Drives Escape from mRNA Vaccine-Induced Humoral Immunity Academic Background Since its emergence in late 2019, SARS-CoV-2 has undergone continuous evolution, giving rise to multiple variants. These variants have enhanced their transmissibility and immune evasion capabilities through mutations, particularly agains...

Multi-modal Analysis Reveals Tumor and Immune Features Distinguishing EBV-Positive and EBV-Negative Post-Transplant Lymphoproliferative Disorders

Medicine, Infectious Diseases, Oncology, Life Sciences, Cell Biology, Immunology,
EBV-positive   post-transplant lymphoproliferative disorders   tumor microenvironment   CD300A   multi-omics analysis  

Report on the Academic Paper: “Multi-modal Analysis Reveals Tumor and Immune Features Distinguishing EBV-positive and EBV-negative Post-transplant Lymphoproliferative Disorders” Summary The Epstein-Barr virus (EBV) is a widely disseminated gamma-1 herpesvirus that infects approximately 90%-95% of adults globally. While EBV infection is typically as...

Structure-Guided Development of Selective Caseinolytic Protease P Agonists as Antistaphylococcal Agents

Chemistry, Medicinal Chemistry, Medicine, Infectious Diseases, Pharmacy, Life Sciences, Biochemistry, Microbiology,
Caseinolytic Protease P   Antistaphylococcal Agents   ZG297   MRSA   Structure-Guided Design   Selective Agonists   Antibiotics  

Structure-Guided Development of Selective Caseinolytic Protease P Agonists as Antistaphylococcal Agents Academic Background Staphylococcus aureus is a common Gram-positive pathogen that can cause various human infections, including skin and soft tissue infections. With the widespread dissemination of methicillin-resistant Staphylococcus aureus (MRS...