Robust Encoding of Stimulus-Response Mapping by Neurons in Visual Cortex Academic Background In the field of neuroscience, the visual cortex is considered a core area for processing visual information. The traditional view holds that neurons in the visual cortex primarily encode perceptual-related information, such as the location, shape, and color...

As the global aging problem intensifies, the incidence of neurodegenerative diseases (such as Alzheimer’s Disease, AD) is increasing year by year. Brain aging (Brain Aging, BA) is one of the significant risk factors for neurodegenerative diseases, but it does not completely align with chronological age (Chronological Age, CA). Traditional methods f...

The Detrimental Role of Arginase-1 in Macrophages After Ischemic Stroke Academic Background Ischemic stroke remains one of the leading causes of long-term disability worldwide. Although arginase-1 (Arg1) is typically associated with anti-inflammatory responses and tissue repair, its specific role in post-stroke recovery remains unclear. Arg1 is pre...

The Role of Notch, ERK, and SHH Signaling Pathways in the Fate Determination of Cortical Glial Cells and Olfactory Bulb Interneurons Academic Background During cortical development, neurogenesis and gliogenesis are two closely connected stages. Neurogenesis primarily generates neurons, while gliogenesis produces glial cells, including astrocytes an...

Correlation between PTDP-43 Levels and Cell-Specific Molecular Alterations in the Prefrontal Cortex of C9orf72 ALS/FTD Patients Background Introduction Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are two types of progressive neurodegenerative diseases. Their common feature is the loss of specific neuronal populations in th...

Analysis of Pelvis and Lower Limb Coordination in Stroke Patients Using Smartphone-Based Motion Capture Technology Academic Background Stroke is one of the diseases with the highest incidence, disability, and mortality rates worldwide, with up to 15 million new cases each year. Among them, 20%-30% of stroke patients develop hemiplegic gait, which i...