Dual Functions of Pericytes and Perivascular Fibroblasts in Cerebrovascular Regeneration After Stroke Academic Background Stroke is one of the leading causes of death and disability worldwide. Current therapeutic interventions are mostly limited to acute thrombolytic treatment or thrombectomy, followed by long-term rehabilitation. However, the long...

Inferring Latent Neural Circuits from Heterogeneous Neural Responses During Cognitive Tasks Academic Background In cognitive tasks, higher cortical areas of the brain (such as the prefrontal cortex, PFC) are responsible for integrating a variety of sensory, cognitive, and motor signals. However, the responses of individual neurons often exhibit com...

Separating Cognitive and Motor Processes: A Breakthrough in Mouse Behavioral Research Academic Background In the study of animal behavior, cognitive processes and motor processes are often closely intertwined. For example, when a mouse explores its environment, its facial expressions or active sampling behaviors not only reflect movement but are al...

Exploration of the Architecture of the Human Default Mode Network: A Study Based on Cytoarchitecture, Wiring, and Signal Flow Academic Background The Default Mode Network (DMN) is a set of brain regions that are highly active during resting states, primarily distributed across the frontal, temporal, and parietal lobes. The DMN plays a crucial role ...

Neural Mechanisms of Visual Perception and Motor Coordination Academic Background In daily life, animals need to distinguish sensory experiences caused by the external environment from those elicited by their own movements. This distinction is crucial for accurate perception and motor control. However, the diversity of behaviors and their complex i...

Retrieval of Conditioned Immune Response in Mice is Mediated by an Anterior-Posterior Insular Circuit Academic Background The bidirectional relationship between the brain and the immune system is a cornerstone of philosophical and scientific research. In recent years, researchers have identified multiple pathways through which the immune system inf...