A Novel Method to Study CSF Flow and BOLD Coupling Using Real-Time Phase Contrast Interleaved with Cortical BOLD MRI

Medicine, Neurology, Medical Imaging, Life Sciences, Biophysics,
CSF flow   real-time phase contrast   BOLD   glymphatic system   brain clearance   BOLD-CSF coupling  

New Method for Studying the Coupling Between Cerebrospinal Fluid Flow and Cortical BOLD Signals Academic Background In recent years, the role of cerebrospinal fluid (CSF) in brain waste clearance has garnered significant attention. Traditionally, CSF was thought to primarily serve as a cushion and provide immune surveillance. However, growing evide...

Choroid Plexus Aging: Structural and Vascular Insights from the HCP-Aging Dataset

Medicine, Geriatrics, Neurology, Medical Imaging,
choroid plexus   aging   human connectome project   perfusion function   vascular degeneration  

Research on Choroid Plexus Aging and Cerebrospinal Fluid Dynamics Background Introduction The choroid plexus (CHP) is a highly vascularized structure located within the brain ventricles, primarily responsible for the production of cerebrospinal fluid (CSF) and the clearance of metabolic waste. It plays a crucial role in maintaining neurofluid homeo...

Lumped Parameter Simulations of Cervical Lymphatic Vessels: Dynamics of Murine Cerebrospinal Fluid Efflux from the Skull

Physics, Fluid Physics, Engineering, Mechanical Engineering, Medicine, Neurology,
cervical lymphatic vessels   lymphatic system   cerebrospinal fluid   traumatic brain injury   numerical simulation   fluid dynamics   intracranial pressure  

Numerical Simulation Study of Cerebrospinal Fluid Drainage through Cervical Lymphatic Vessels Background Introduction Cerebrospinal fluid (CSF) is a clear fluid that circulates around the brain and spinal cord, providing physical protection, nutrient supply, and waste clearance for the central nervous system. In recent years, growing evidence sugge...

Development and Application of an Automated In Vitro Model for Hydrocephalus Research

Medicine, Neurology, Life Sciences, Bioengineering,
hydrocephalus   in vitro modeling   cerebrospinal fluid flow pattern   CSF dynamics   microfluidic   pump   bioreactor  

Application of Automated In Vitro Models in Hydrocephalus Research Background Introduction Hydrocephalus is a neurological condition caused by the accumulation of cerebrospinal fluid (CSF) in the brain’s ventricles. If left untreated, it can lead to severe complications and permanent brain damage. It is estimated that 1 in every 500 newborns is bor...

Numerical Study of the Effects of Minor Structures and Mean Velocity Fields in the Cerebrospinal Fluid Flow

Physics, Fluid Physics, Engineering, Mechanical Engineering, Medicine, Neurology, Life Sciences, Bioengineering,
cerebrospinal fluid   intrathecal injection   computational fluid dynamics   lagrangian velocity   spinal subarachnoid space   fluid transport   geometric variability  

Study on Cerebrospinal Fluid Flow Dynamics and Its Application in Drug Delivery Background Introduction Cerebrospinal fluid (CSF) plays a crucial role in the human spinal canal, responsible for transporting dissolved nutrients and waste products. Due to its pulsatile nature, CSF flow is influenced by cardiac and respiratory cycles. In recent years,...

Association between Choroid Plexus Volume and Cognitive Function in Community-Dwelling Older Adults without Dementia: A Population-Based Cross-Sectional Analysis

Medicine, Geriatrics, Neurology, Medical Imaging,
choroid plexus   cognitive function   older adults   cerebrospinal fluid   cross-sectional analysis   dementia   brain imaging  

Association Between Choroid Plexus Volume and Cognitive Function in Community-Dwelling Older Adults: A Research Study Academic Background With the increasing global aging population, the number of dementia patients is rising annually. Early identification of older adults with declining cognitive function and guiding them toward preventive and thera...