Classification Study of Parkinson’s Disease and Cervical Dystonia Academic Background Parkinson’s Disease (PD) and Cervical Dystonia (CD) are two common movement disorders whose pathological mechanisms are closely related to abnormal neuronal activity in the basal ganglia. The basal ganglia are a crucial brain structure for motor control, with the ...
The Role of 5-HT1A Agonist Buspirone in Pain Regulation in Postcolitis Rats Background In recent years, increasing clinical and experimental evidence has shown that the brain’s serotonin (5-HT) system plays a significant role in the pathogenesis of gastrointestinal disorders, such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IB...
Distribution and Function of CB1 Cannabinoid Receptor and VGLUT3 in the Human Cerebral Cortex Background Cannabinoid receptor 1 (CB1) regulates synaptic transmission through presynaptic receptors in nerve terminals, and its physiological roles are of significant clinical relevance. However, the cellular sources and synaptic targets of CB1-expressin...
Study on Structural and Functional Network Connectivity Changes in Patients with Traumatic Brain Injury Background Introduction Traumatic Brain Injury (TBI) is a common neurological disorder that can lead to long-term cognitive, emotional, and physical symptoms. Although many patients experience symptom relief within months after the injury, a sign...
Effects of Altered Haptic Feedback Gain on Balance and Its Neural Mechanisms Background In daily life, human balance control relies on multiple sensory inputs, including vision, vestibular sensation, and proprioception. Haptic feedback also plays a crucial role in balance control, especially when touching a fixed object, as it significantly reduces...
Detection of Target Odorants in Odor Mixtures Among Healthy Individuals and Patients with Olfactory Dysfunction Academic Background In daily life, most of the odors we encounter are mixtures rather than single odorants. However, the mechanisms underlying human perception of odor mixtures are far less understood than those of single odorants. The pe...
The Effect of Transcranial Magnetic Stimulation Inter-Pulse Interval on Corticospinal Excitability of the Biceps Brachii Research Background Transcranial Magnetic Stimulation (TMS) is a non-invasive neurophysiological research technique widely used to assess corticospinal excitability in both healthy individuals and clinical patients. By applying e...
Reorganization of Topological Features in Brain Functional Networks in Patients with Chronic Tinnitus Academic Background Tinnitus is the perception of sound in the absence of any external acoustic stimuli or internal sources of auditory perception, with a global prevalence ranging from 11.9% to 30.3%. Patients with tinnitus experience not only aud...
Study on Laser-Induced Olfactory Bulbectomy in Zebrafish as a Novel Model for Affective Syndrome Background Affective disorders, such as depression, are common mental health issues worldwide. Although rodent models have played a significant role in depression research, their cross-species applicability has limitations. Zebrafish (Danio rerio), as a...
The Interaction Between A2A Receptor and CB1 Receptor in GABA and Glutamate Release in the Basal Ganglia Background The basal ganglia are key structures in the brain responsible for motor control and reward-based behaviors. They receive excitatory inputs from the cortex and thalamus, with 80% of the synapses being glutamatergic, while the second mo...