Assessing the Global Burden of Mesothelioma: Trends, Socioeconomic Influences, and Asbestos Exposure – A Retrospective Cohort Study

Global Burden Assessment of Mesothelioma – Trends, Socioeconomic Influences, and Asbestos Exposure Academic Background Mesothelioma is a rare form of cancer that primarily affects the lining of the lungs (pleura) but can also occur in the lining of the abdominal cavity (peritoneum), heart, or testicles. Due to its rarity and long latency period, me...

Evaluating the Effectiveness of Cytoreductive Surgery in Oligometastatic Prostate Cancer: Insights from Quantitative Analysis and Retrospective Cohort Studies

Evaluating the Effectiveness of Cytoreductive Surgery in Oligometastatic Prostate Cancer Academic Background Prostate cancer is the second most common malignancy among men globally, particularly in its advanced stages, where it is often accompanied by metastases, significantly impacting patients’ quality of life and prognosis. Oligometastatic prost...

Hepatic Arterial Infusion Chemotherapy-Based Conversion Hepatectomy in Responders Versus Nonresponders with Hepatocellular Carcinoma: A Multicenter Cohort Study

Hepatic Arterial Infusion Chemotherapy (HAIC)-Based Conversion Hepatectomy in Patients with Hepatocellular Carcinoma Academic Background Hepatocellular carcinoma (HCC) is one of the most common liver malignancies worldwide, particularly in China, where its incidence and mortality rates remain high. Despite advancements in treatment strategies, radi...

Global, Regional, and National Burdens of Mild Traumatic Brain Injuries from 1990 to 2019: Findings from the Global Burden of Disease Study 2019 – A Cross-Sectional Study

Global Burden of Mild Traumatic Brain Injury: 1990-2019 Academic Background Mild traumatic brain injury (MTBI) is a common global health issue, particularly prevalent among the elderly population. MTBI not only causes symptoms such as headaches, dizziness, and fatigue but may also lead to long-term cognitive impairments, mood swings, and sleep diso...

Early-Life Malnutrition Exposure Associated with Higher Osteoporosis Risk in Adulthood: A Large-Scale Cross-Sectional Study

Early Malnutrition and the Risk of Osteoporosis in Adulthood: A Large-Scale Cross-Sectional Study Academic Background Osteoporosis is a chronic, systemic metabolic bone disease characterized by reduced bone density and deterioration of bone microstructure, leading to a significantly increased risk of fractures. Globally, approximately 9 million fra...

Adverse Complications of Cervical Spinal Fusion in Patients with Different Types of Diabetes Mellitus: A Retrospective Nationwide Inpatient Sample Database Cross-Sectional Study

Postoperative Complications of Cervical Spinal Fusion in Diabetic Patients: A Retrospective Study Background Diabetes Mellitus (DM) is a globally prevalent chronic condition that significantly impacts surgical outcomes, particularly in spine surgery. Diabetic patients face a higher risk of postoperative complications. However, over the past decade,...

Observational Cohort Study on Safety and Efficacy of Robotic Thyroidectomy with Super-Meticulous Capsular Dissection versus Open Surgery for Thyroid Cancer: Postoperative Dynamic Risk Assessment of Radioactive Iodine Therapy

Comparative Study of Robotic-Assisted Thyroidectomy versus Traditional Open Surgery in Thyroid Cancer Treatment Academic Background The incidence of thyroid cancer has been increasing annually, with differentiated thyroid carcinoma (DTC) accounting for over 90% of all thyroid cancer cases. Currently, the standard treatment for DTC includes surgical...

Reoperation for Ipsilateral Local Recurrence Following Prior Nephron-Sparing Surgery: Innovative Surgical Insights from a High-Volume Urological Center with Cross-Sectional Study

Innovative Surgical Strategies for Reoperation of Local Recurrence in Renal Cell Carcinoma Academic Background Renal cell carcinoma (RCC) is one of the most common malignant tumors in adults, accounting for 5% of malignancies in males and 3% in females. Although surgery remains the standard treatment for localized RCC, nephron-sparing surgery (NSS)...

Investigating the Validity of MCIM and SCIM Phenotypic Methods in Screening Pseudomonas aeruginosa Isolates Producing IMP, VIM, and NDM Metallo-Beta-Lactamases Isolated from Burn Wounds

Investigating the Validity of mCIM and sCIM Phenotypic Methods in Screening Pseudomonas aeruginosa Isolates Producing IMP, VIM, and NDM Metallo-β-Lactamases from Burn Wounds Background Pseudomonas aeruginosa is a Gram-negative bacterium widely found in the environment, particularly in hospital settings. It is the second most common pathogen causing...

Aztreonam-Avibactam: A New Combination with Activity Against Multidrug-Resistant Klebsiella pneumoniae Complex

Aztreonam-Avibactam Activity Against Multidrug-Resistant Klebsiella pneumoniae Complex Background The Klebsiella pneumoniae complex (KPC) is a group of opportunistic pathogens that pose a serious threat to public health. In recent years, the infection rate of multidrug-resistant (MDR) Klebsiella pneumoniae has significantly increased, leading to ex...