Targeted Delivery of Napabucasin with Radiotherapy Improves Outcomes in Diffuse Midline Glioma

Medicine, Neurology, Oncology,
Diffuse Midline Glioma   Radiotherapy   Napabucasin   Targeted Delivery   Blood-Brain Barrier   Oxidative Stress   Survival Rate  

Targeted Delivery of Napabucasin with Radiotherapy in Diffuse Midline Glioma Background Introduction Diffuse Midline Glioma (DMG) is the most aggressive primary brain tumor in children, with a median survival typically less than one year. Although radiation therapy (RT) is the current standard treatment, it only provides transient symptom relief an...

Prospective Longitudinal Analysis of Physiologic MRI-Based Tumor Habitat Predicts Short-Term Patient Outcomes in IDH-Wildtype Glioblastoma

Medicine, Neurology, Neurosurgery, Medical Imaging, Oncology,
glioblastoma   tumor habitat   physiologic MRI   prognosis prediction   IDH-wildtype  

Prospective Longitudinal Analysis of Physiologic MRI-Based Tumor Habitat Predicts Short-Term Patient Outcomes in IDH-Wildtype Glioblastoma Academic Background Glioblastoma (GBM) is a highly malignant brain tumor characterized by significant intratumoral heterogeneity, which is evident not only in gene expression and histopathology but also in macro...

ABVS Breast Tumour Segmentation via Integrating CNN with Dilated Sampling Self-Attention and Feature Interaction Transformer

Information Science, Artificial Intelligence, Medicine, Medical Imaging,
Breast Tumour Segmentation   Automated Breast Volume Scanner   3D Transformer-CNN Segmentation Network   Mask Image Modelling   Deep Learning   Medical Image Analysis   Self-Supervised Learning  

ABVS Breast Tumor Segmentation Research Based on CNN and Dilated Sampling Self-Attention Academic Background Breast cancer is the second most common cancer worldwide, and early and accurate detection is crucial for improving patient prognosis and reducing mortality. Although various imaging techniques (such as X-ray mammography, magnetic resonance ...

Comprehensive Evaluation of Pipelines for Classification of Psychiatric Disorders Using Multi-Site Resting-State fMRI Datasets

Comprehensive Evaluation of Pipelines for Classification of Psychiatric Disorders Using Multi-Site Resting-State fMRI Datasets

Medicine, Psychiatry, Neurology, Medical Imaging,
classification biomarker   pipeline   generalization   fMRI   multi-site dataset   major depressive disorder  

Background Introduction The field of psychiatry has long relied on symptoms and medical interviews for diagnosis, lacking objective biomarkers. Resting-state functional magnetic resonance imaging (rs-fMRI) is widely believed to reveal characteristic patterns of brain structure and function, thereby providing potential classification markers for the...

Anxiety Disorder Identification with Biomarker Detection through Subspace-Enhanced Hypergraph Neural Network

Anxiety Disorder Identification with Biomarker Detection through Subspace-Enhanced Hypergraph Neural Network

Information Science, Artificial Intelligence, Medicine, Psychiatry, Medical Imaging, Life Sciences, Bioengineering,
anxiety disorder   hypergraph neural network   multimodal data   subspace enhancement   biomarker  

Anxiety Disorder Identification and Biomarker Detection Based on Subspace-Enhanced Hypergraph Neural Network Academic Background Anxiety Disorders (ADs) are prevalent mental health issues globally, affecting approximately 7.3% of the population. Patients with anxiety disorders typically exhibit excessive fear, worry, and related behavioral abnormal...

Inhibiting Cell Inspection Points Intervention via Injectable Short Fibers for Reversing Neural Cell Senescence

Medicine, Neurology, Neurosurgery, Life Sciences, Cell Biology, Biochemistry, Bioengineering,
neural cell senescence   inspection point   short fibers   spinal cord   genome homeostasis  

Background Introduction Spinal Cord Injury (SCI) is a significant challenge in the medical field, particularly in terms of neural function recovery. Research indicates that neurons play a crucial role in spinal cord regeneration, but in complex pathological environments, neurons are influenced by various factors, leading to rapid senescence. Senesc...