Mechanisms and Research Models of Kidney Fibrosis: Progress Toward Physiologically Relevant Humanized Models Research Background and Problem Statement Chronic Kidney Disease (CKD) is a major global public health issue, estimated to affect more than 10% of the population and is one of the leading causes of mortality. Kidney fibrosis, as a key pathol...

Breakthrough in Next-Generation Oral Ulcer Management: Integration of Cold Plasma and Nanogel Pharmaceutical Systems Background Oral ulcers are one of the most common mucosal diseases, significantly affecting patients’ quality of life. According to epidemiological data, approximately 27.9% of adults suffer from oral ulcers. While these lesions ofte...

A Novel Dual-Pipeline Lactate Removal Strategy for Sepsis Treatment Background Sepsis, defined as multi-organ dysfunction caused by a dysregulated host immune response to bloodborne infection, remains a severe global public health issue. Despite advances in modern medicine, the diagnosis and treatment of sepsis pose significant challenges. Statisti...

Choline Phosphate-Based Antigen Capture Strategy Boosts In Situ Tumor Vaccine Research: A Novel Immunotherapy Approach In the field of cancer immunotherapy, in situ tumor vaccines have garnered significant attention for their ability to harness a patient’s immune system to target tumors. However, challenges remain in their clinical application. To ...

Academic Report on “Bioprinting Perfusable and Vascularized Skeletal Muscle Flaps for the Treatment of Volumetric Muscle Loss” Background Muscle tissues constitute a significant portion of human cellular mass and are a complex, highly vascularized, and dynamic tissue. However, traumatic or surgical Volumetric Muscle Loss (VML)—defined as the loss o...