Towards Machine Learning-Based Quantitative Hyperspectral Image Guidance for Brain Tumor Resection

Towards Machine Learning-Based Quantitative Hyperspectral Image Guidance for Brain Tumor Resection

Information Science, Computer Science, Artificial Intelligence, Medicine, Medical Laboratory Science, Neurology, Neurosurgery, Medical Imaging,
brain tumor   hyperspectral imaging   surgical guidance   machine learning   fluorescence markers  

Study on the Role of Machine Learning-Assisted Quantitative Hyperspectral Imaging in Brain Tumor Resection Background Introduction Complete resection of malignant gliomas has always been challenged by the difficulty of distinguishing tumor cells in invasive regions. The background of this study is: In neurosurgery, the application of 5-aminolevulin...

The Mediating Role of Systemic Inflammation and Moderating Role of Racialization in Disparities in Incident Dementia

Medicine, Environmental and Public Health, Medical Laboratory Science, Geriatrics, Neurology, Clinical Psychology,
Systemic Inflammation   Racialization   Dementia   C-reactive protein   Racial disparities  

The Mediating Role of Systemic Inflammation in the Differences in Cognitive Disease Incidence and the Moderating Role of Racialization This study examines the link between systemic racism and the increased burden of cognitive disease. Researchers investigated the mediating role of C-reactive protein (CRP) as a marker of systemic inflammation in the...

A Single-Nuclei Paired Multiomic Analysis of the Human Midbrain Reveals Age- and Parkinson’s Disease–Associated Glial Changes

A Single-Nuclei Paired Multiomic Analysis of the Human Midbrain Reveals Age- and Parkinson’s Disease–Associated Glial Changes

Medicine, Basic Medical Sciences, Neurology, Life Sciences, Cell Biology, Biochemistry, Immunology,
Parkinson's disease   single-nuclei paired analysis   multiomic analysis   human midbrain   age-related changes   glial cells   chromatin accessibility  

Single-nucleus Multi-omics Analysis Reveals Age-related and Parkinson’s Disease-related Changes in Neuroglia in the Human Midbrain Research Background Age is a major risk factor for Parkinson’s Disease (PD). Although the significant role of age in PD onset is known, details about how age alters the gene expression and regulatory landscape of the br...

Mediterranean diet and associations with the gut microbiota and pediatric-onset multiple sclerosis using trivariate analysis

Medicine, Neurology, Life Sciences,
Mediterranean diet   gut microbiota   pediatric-onset   multiple sclerosis   trivariate analysis  

Research Report: Ternary Analysis of Mediterranean Diet, Gut Microbiota, and Juvenile Onset Multiple Sclerosis Research Background Multiple Sclerosis (MS) is an autoimmune disease in which the immune system attacks the protective layer of nerve cells. Numerous studies have indicated that environmental risk factors, such as low vitamin D levels and ...

Single-Nucleus Sequencing Reveals Enriched Expression of Genetic Risk Factors in ALS-Sensitive Neurons

Medicine, Basic Medical Sciences, Geriatrics, Neurology, Life Sciences, Biochemistry, Genetics,
single-nucleus sequencing   ALS   neurons   genetic risk factors   transcriptomics  

Publication of a New Study on ALS Neurodegeneration in 《Nature Aging》 Throughout human history, numerous mysterious diseases have posed significant challenges for scientific research. Among these, Amyotrophic Lateral Sclerosis (ALS), a progressive neurodegenerative disease, is known for the gradual loss of muscle function and disability it causes. ...

Restoration of Neuronal Progenitors by Partial Reprogramming in the Aged Neurogenic Niche

Medicine, Geriatrics, Neurology, Life Sciences, Cell Biology, Biochemistry, Genetics,
Partial Reprogramming   Neuronal Progenitors   Aged Neurogenesis   Single-Cell Transcriptomics   SVZ Neurogenic Niche  

Scientific Research Report Background Introduction For a long time, aging has been considered an irreversible process. However, recent research suggests that aging is a biological process that can be regulated. Various interventions have been shown to delay or even reverse certain characteristics of aging. Partial reprogramming is a method that rev...