Enabling Explainable Artificial Intelligence for Glioma Prognosis: Translational Insights from Transparent Machine Learning Academic Background This study is dedicated to developing a reliable technique to detect whether patients have a specific type of brain tumor—glioma—using various machine learning methods and deep learning methods, combined wi...
Survival Analysis of Glioblastoma Patients: An Overview Empowered by Data Engineering Introduction Glioblastoma is a type of tumor that occurs in glial cells and accounts for 26.7% of all primary brain and central nervous system tumors. Survival analysis of glioblastoma patients is a key task in clinical management due to the heterogeneity of the t...
Personalized Prediction of Glioma Growth Using Bayesian Inference Introduction Glioblastoma is the most aggressive type of primary brain tumor, characterized by highly invasive tumor cells that spread to surrounding tissues. Conventional medical imaging techniques cannot precisely identify these diffuse tumor boundaries, leading to suboptimal clini...
Numerical Analysis of Rectangular Open-Channel PCF Biosensor Embedded with TiO2-Au-MXene for Brain Tumor Diagnosis Academic Background and Problem Statement In recent years, the development of cost-effective and highly reliable biosensors has become a research hotspot. These sensors aim to detect minute concentrations of analytes and cover a wide a...
Comparison of Acoustic Patterns and Microbubble Delivery Strategies in Large-Volume Drug Delivery Mediated by Focused Ultrasound for Blood-Brain Barrier Opening Background Diffuse Intrinsic Pontine Glioma (DIPG) is the most common and lethal brainstem tumor in children. Due to the usually intact blood-brain barrier (BBB) in DIPG, drug penetration i...
The research results, completed in collaboration by many scientists including Lishu Chen, Qinghui Qi, and Xiaoqing Jiang, were published in the groundbreaking journal Cancer Discovery. The report detailed how phosphocreatine (PCr) promotes the growth of glioblastoma (GBM) by stabilizing bromodomain-containing protein 2 (BRD2). This discovery provid...