Impact of Truck Electrification on Air Pollution Disparities in the United States

Engineering, Environmental Engineering, Transportation Engineering, Energy Engineering, Medicine, Environmental and Public Health,
truck electrification   air pollution   United States   environmental justice   emission reduction   health impacts   grid decarbonization  

Academic Background As global climate change intensifies and air pollution becomes increasingly severe, reducing carbon emissions and pollutant emissions in the transportation sector has become a focus for governments and research institutions worldwide. Heavy-duty trucks (Class 8), as the primary means of freight transport in the United States, co...

Economic Costs of Wind Erosion in the United States

Earth Sciences, Atmospheric Science, Engineering, Environmental Engineering, Medicine, Environmental and Public Health,
wind erosion   economic costs   climate change   health impacts   renewable energy   transportation   agricultural loss  

Wind erosion and the resulting dust issues have profound impacts on the environment and human society. Since the 1990s, despite significant changes in climate and socioeconomic conditions, the United States has not conducted a comprehensive assessment of the economic costs of wind erosion. In recent years, with global warming, increasing droughts, ...

Rising Socio-Economic Costs of PM2.5 Pollution and Medical Service Mismatching

Rising Socio-Economic Costs of PM2.5 Pollution and Medical Service Mismatching

Engineering, Environmental Engineering, Medicine, Environmental and Public Health, Geriatrics,
PM2.5 pollution   medical service mismatching   socio-economic costs   ageing society   health impacts  

Academic Background As global population ageing intensifies, the impact of air pollution on public health becomes increasingly significant. Fine particulate matter (PM2.5) pollution is recognized as a major factor contributing to health issues such as cardiovascular diseases, chronic respiratory illnesses, and cognitive impairments. Particularly in...

Targeting ADAR1 with a Small Molecule for the Treatment of Prostate Cancer

Chemistry, Medicinal Chemistry, Medicine, Urology, Pharmacy, Oncology,
prostate cancer   ADAR1   small molecule inhibitor   tumor immunity   RNA editing  

Academic Background Prostate cancer (PCA) is one of the most common malignancies in men, particularly in Western countries, where it is the second leading cause of cancer-related deaths among males. Although androgen signaling therapy is effective in the initial treatment of prostate cancer, most patients eventually relapse, and there is currently ...

Microbiome Dysbiosis, Neutrophil Recruitment and Mesenchymal Transition of Mesothelial Cells Promotes Peritoneal Metastasis of Colorectal Cancer

Medicine, Gastroenterology, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology,
microbiome dysbiosis   neutrophil recruitment   mesothelial cells   mesenchymal transition   colorectal cancer   peritoneal metastasis   tumor microenvironment  

Background Introduction Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide, with high incidence and mortality rates. According to statistics, approximately 1.87 million new cases of CRC were diagnosed globally in 2020, resulting in 915,000 deaths. Peritoneal metastasis (PM) is a common metastatic pathway of CRC, with about ...

Neutrophils Physically Interact with Tumor Cells to Form a Signaling Niche Promoting Breast Cancer Aggressiveness

Medicine, Oncology, Life Sciences,
Neutrophils   Breast Cancer   Signaling Niche   Tumor Microenvironment   Single-Cell RNA Sequencing  

Academic Background Breast cancer is one of the most common malignant tumors among women worldwide, with a complex pathogenesis involving interactions among multiple cell types and signaling pathways. In recent years, the role of the tumor microenvironment (TME) in cancer progression has gradually gained attention. Neutrophils, as an essential comp...