Arabinoxylan-Incorporated Poly(ε-Caprolactone) Nanofiber Matrix Promotes Fibroblast Cell Adhesion and Proliferation

Chemistry, Nanoscience, Polymer Chemistry, Chemical Engineering, Materials Science, Organic Polymeric Materials, Medicine, Life Sciences, Bioengineering,
Nanofibrous matrix   Arabinoxylan   Fibroblasts   Cell adhesion   Cell proliferation  

Academic Background Wound healing is a complex physiological process involving multiple coordinated stages, including hemostasis, inflammation, proliferation, and remodeling. However, in cases of severe trauma or chronic wounds, traditional treatments such as dressings and sutures often have limited efficacy. In recent years, the development of tis...

Synthesis, Physicochemical Characterization, and Antimicrobial Evaluation of Ureasil-Polyether Coatings with Silver Nanoparticles for Hospital Devices

Chemistry, Nanoscience, Polymer Chemistry, Materials Science, Inorganic Non-Metallic Materials, Medicine, Infectious Diseases, Life Sciences, Bioengineering, Microbiology,
silver nanoparticles   hybrid materials   sol-gel process   hybrid nanocomposite   antimicrobial coatings   hospital devices   physicochemical characterization  

Research Background Nosocomial infections are a common and serious problem in healthcare settings, particularly on reusable medical devices, where cross-contamination and biofilm formation are major causes. To address this challenge, researchers have begun exploring the use of coating materials containing metallic nanoparticles to prevent microbial...

A Novel Formulation of Docetaxel-Containing Micelle Surface Modified with Metronidazole to Target Tumor Hypoxia

Chemistry, Medicinal Chemistry, Medicine, Oncology, Life Sciences, Bioengineering,
tumor hypoxia   metronidazole   active targeting   micelle   docetaxel  

Background Introduction Cancer is one of the leading causes of death globally, and despite significant progress in treatment, the complexity of tumors, particularly tumor hypoxia, remains a major obstacle to successful therapy. Hypoxic regions are prevalent in solid tumors, where oxygen concentrations are significantly lower than in normal tissues ...

Tissue Engineered Scaffolds Combined with Exercise in the Treatment of Volumetric Muscle Loss in Rat Model

Chemistry, Nanoscience, Materials Science, Medicine, Sports Medicine, Life Sciences, Bioengineering,
Volumetric Muscle Loss   Polycaprolactone   Silver Nanoparticle   Decellularized Human Amniotic Membrane   Exercise  

Academic Background Volumetric Muscle Loss (VML) is a severe muscle injury typically caused by trauma, ischemia, or tumor excision. VML leads to irreversible loss of muscle fibers, resulting in fibrosis, deformity, and long-term dysfunction. Unlike ordinary muscle injuries, VML has very limited regenerative capacity because the extent of damage exc...

Attractive Investigation of Zinc Chromium Nanoferrite by a Simple Auto-Combustion Method

Chemistry, Nanoscience, Materials Chemistry, Materials Science, Inorganic Non-Metallic Materials, Medicine, Infectious Diseases, Life Sciences, Biochemistry, Bioengineering, Microbiology,
nanoferrite   structural properties   magnetic properties   antimicrobial activity  

Synthesis and Study of Antimicrobial and Magnetic Properties of ZnFeCrO4 Nanoferrite Academic Background Nanoferrites, due to their unique physical and chemical properties, have broad application prospects in various industrial fields. Spinel ferrites, in particular, are highly regarded for their tunable structures, making them attractive for use i...

Sugarcane Wax-Based Solid Lipid Nanoparticles as an Atorvastatin Carrier: Characterization and In Vivo Evaluation of Antihyperlipidemic Activity in Rats

Chemistry, Medicinal Chemistry, Medicine, Pharmacy, Cardiovascular System,
Sugarcane wax   Solid lipid nanoparticles   Atorvastatin   In vivo studies   Antihyperlipidemic  

Academic Background Cardiovascular diseases, particularly atherosclerosis, are one of the leading causes of death globally. Elevated cholesterol levels are a major risk factor for atherosclerosis. Atorvastatin (ATV) is a widely used cholesterol-lowering drug, but its oral bioavailability is low, primarily due to first-pass metabolism. To improve th...