The Association of Physical Activity Fragmentation with All-Cause Mortality in Hispanics: A Prospective Cohort Study

Research Background and Question In modern society, the patterns of physical activity (PA) and their impact on health have been a critical area of public health and medical research. Traditional studies have primarily focused on the total volume and intensity of physical activity. However, in recent years, an increasing number of studies have begun...

The Inflammatory Landscape of a Whole-Tissue Explant Model of Hidradenitis Suppurativa

Research Background Current Status and Challenges in Hidradenitis Suppurativa Research Hidradenitis Suppurativa (HS) is a relatively common and highly morbid inflammatory skin disease. It affects approximately 1% of the global population, disproportionately impacting women and marginalized groups. HS’s pathogenesis is complex, involving genetic, im...

Development and Validation of a Time-Varying Correction Factor for QT Interval Assessment in Drug-Resistant Tuberculosis Patients

Development and Validation of a Time-Varying Correction Factor for QT Interval Assessment in Drug-Resistant Tuberculosis Patients Academic Background and Research Motivation During the treatment of active tuberculosis (Tuberculosis, TB), patients often experience tachycardia (Tachycardia), which typically diminishes as they recover. Elevated heart ...

The Role of Electroencephalography in Epilepsy Research—From Seizures to Interictal Activity and Comorbidities

The Role of Electroencephalography in Epilepsy Research: From Seizures to Interictal Activity and Comorbidities Academic Background Since the early 20th century, electroencephalography (EEG) has been a key tool in epilepsy research. EEG technology not only helps scientists record and analyze brain signals but also reveals the pathophysiological mec...

Neurocritical Care Organization in Low-Income and Middle-Income Countries

Neurocritical Care Organization in Low- and Middle-Income Countries Academic Background and Problem Statement Neurocritical care (NCC) has rapidly evolved over the past few decades as a distinct subspecialty of critical care medicine. Evidence shows that patients with acute brain injuries have significantly improved outcomes when treated in dedicat...

Recommendations for Implementing the HEvolution Alliance for Aging Biomarkers Initiative

Promoting Healthy Longevity: Implementation Recommendations for the Hevolution Alliance for Aging Biomarkers Initiative Academic Background and Research Motivation With the intensification of global population aging, human life expectancy has significantly increased, but the growth in healthy life expectancy (i.e., years lived in good health) has b...